4-((4-(Trifluoromethoxy)phenyl)amino)benzoic acid CAS 617245-21-3
| CAS No. | 617245-21-3 |
| Molecular Formula | C14H10F3NO3 |
| Molecular Weight | 297.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.23 g/mol gives 4-((4-(Trifluoromethoxy)phenyl)amino)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-((4-(Trifluoromethoxy)phenyl)amino)benzoic acid (CAS 617245-21-3), a certified reference material (molecular formula C14H10F3NO3, MW 297.23 g/mol) for analytical method development and quality control.
4-((4-(Trifluoromethoxy)phenyl)amino)benzoic acid (C14H10F3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10F3NO3 |
| Molecular Weight | 297.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 3-(4-(TRifluoromethoxy)phenyl)isonicotinic acid methyl ester (CAS 1261451-16-4)
- 4-(4-(TRifluoromethoxy)phenyl)picolinic acid methyl ester (CAS 1261617-85-9)
- Methyl 3-(3-(trifluoromethoxy)phenyl)isonicotinate (CAS 1261749-20-5)
- Methyl 6-[2-(Trifluoromethoxy)phenyl]nicotinate (CAS 1261782-37-9)
- 3-(4-(Trifluoromethoxy)phenyl)-3h-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol (CAS 1105195-38-7)
- 8-(Trifluoromethoxy)-2-(trifluoromethyl)quinolin-4-ol (CAS 306935-26-2)
- [4-(Trifluoromethoxy)phenyl]-N-(chlorocarbonyl)carbamic acid methyl ester (CAS 173903-15-6)
- (4-(4-(Trifluoromethoxy)phenoxy)phenyl)boronic acid (CAS 958457-41-5)
Recommended Standards
- 4-((2-Oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzoic acid (CAS 339024-98-5)
- 4-Nitro-1-n-[3-(trifluoromethyl)phenyl]benzene-1,2-diamine (CAS 735305-34-7)
- 3-Nitro-N-{[3-(trifluoromethyl)phenyl]methyl}pyridin-2-amine (CAS 339009-88-0)
- 6-Methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxylic acid (CAS 694479-56-6)
- (S)-Apomorphine Hydrochloride (CAS 41035-30-7)
- Ethyl 1-isobutyl-5-methyl-1H-imidazole-4-carboxylate (CAS 1710695-88-7)
- 2-hydrazinyl-3-methylquinoline (CAS 115761-88-1)
- Deferasirox Impurity 18 (CAS 1395346-29-8)
- 2-Isopropyl-1,3-thiazolidine-4-carboxylic acid hydrochloride (CAS 1910806-09-5)
- methyl 7-bromo-1-benzofuran-2-carboxylate (CAS 1247406-14-9)
- 2-(2,3-Dimethylphenoxy)-3,3,3-trifluoropropan-1-amine (CAS 886763-99-1)
- 7-Bromo-2-cyclopropylquinazolin-4(3H)-one (CAS 1693955-94-0)
- 1-Acetyl-4-bromo-3-phenyl-5-(trifluoromethyl)-1H-pyrazole (CAS 1017793-50-8)
- Insulin degludec (CAS 844439-96-9)
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