6-Chloro-2-morpholinoquinazolin-4(1H)-one CAS 61741-54-6
| CAS No. | 61741-54-6 |
| Molecular Formula | C12H12ClN3O2 |
| Molecular Weight | 265.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-morpholinoquinazolin-4(1H)-one (C12H12ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-Chloro-2-morpholinoquinazolin-4(1H)-one (CAS 61741-54-6), molecular formula C12H12ClN3O2 and molecular weight 265.70 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-2-morpholinoquinazolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12ClN3O2 |
| Molecular Weight | 265.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- Ethyl 1-(4-chlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylate (CAS 91396-27-9)
- N-Boc-2-cyano-L-phenylalanine (CAS 216312-53-7)
- 6-Bromo-3-hydroxy-2-(o-tolyl)quinazolin-4(3H)-one (CAS 338774-69-9)
- 1-(6-Nitrobenzo[d][1,3]dioxol-5-yl)piperidine (CAS 893765-34-9)
- 5-Fluoro-2-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)pyridine (CAS 1774896-93-3)
- 1-[(4-Methylphenyl)sulfonyl]-1,4-diazepane hydrochloride (CAS 1582149-10-7)
- 1-[6-(thiophen-2-yl)pyridazin-3-yl]piperidine-4-carboxylic acid (CAS 1017117-60-0)
- Dalbavancin B1 (CAS 171500-82-6)
- 3,5-Dichloro-4-fluorobenzaldehyde (CAS 117820-80-1)
- 3-(3-(Difluoromethyl)-1H-pyrazol-1-yl)propan-1-amine hydrochloride (CAS 1855888-84-4)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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