5-Fluoro-2’-3’-O-isopropylidenecytidine CAS 61787-04-0

Purity 97%+In StockPharmaceutical Standards
CAS No.61787-04-0
Molecular FormulaC12H16FN3O5
Molecular Weight301.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Fluoro-2’-3’-O-isopropylidenecytidine CAS 61787-04-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 301.27 g/mol gives 5-Fluoro-2’-3’-O-isopropylidenecytidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Fluoro-2’-3’-O-isopropylidenecytidine (CAS 61787-04-0) is a high-purity analytical reference standard with the molecular formula C12H16FN3O5 and a molecular weight of 301.27 g/mol.

Structurally, 5-Fluoro-2’-3’-O-isopropylidenecytidine (C12H16FN3O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 301.27 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Fluoro-2’-3’-O-isopropylidenecytidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H16FN3O5
Molecular Weight301.27 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1974
Halogen ContentF-containing
Nitrogen Atoms3

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