4-(2,3-Dihydrobenzo[b][1,4]dioxine-6-carbonyl)-3-hydroxy-1-(2-morpholinoethyl)-5-(pyridin-3-yl)-1H-pyrrol-2(5H)-one CAS 618071-69-5
| CAS No. | 618071-69-5 |
| Molecular Formula | C24H25N3O6 |
| Molecular Weight | 451.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(2,3-Dihydrobenzo[b][1,4]dioxine-6-carbonyl)-3-hydroxy-1-(2-morpholinoethyl)-5-(pyridin-3-yl)-1H-pyrrol-2(5H)-one (CAS 618071-69-5) is a high-purity analytical reference standard with the molecular formula C24H25N3O6 and a molecular weight of 451.47 g/mol.
The molecular framework of 4-(2,3-Dihydrobenzo[b][1,4]dioxine-6-carbonyl)-3-hydroxy-1-(2-morpholinoethyl)-5-(pyridin-3-yl)-1H-pyrrol-2(5H)-one (C24H25N3O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H25N3O6 |
| Molecular Weight | 451.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
Related Dihydrobenzo Standards
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- Ethyl 2-((2-(2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl)-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy)propanoate (CAS 868224-64-0)
- 2-(1-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl 2-(methylthio)nicotinate (CAS 744229-66-1)
- 2-((2,3-Dihydrobenzo[b][1,4]dioxine)-6-sulfonamido)-N-(2-methoxyethyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 852932-33-3)
- 3-((4-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)-1,4-diazepan-1-yl)sulfonyl)aniline (CAS 1203494-49-8)
- 1-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)-4-((4-methoxyphenyl)sulfonyl)piperazine (CAS 562867-96-3)
- 1-(4-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)piperazin-1-yl)-2-(6-methylbenzofuran-3-yl)ethan-1-one (CAS 847939-23-5)
- 3-((2,3-Dihydrobenzo[b][1,4]dioxine)-6-sulfonamido)-N-(2-oxo-2-(piperidin-1-yl)ethyl)benzamide (CAS 1111446-79-7)
Recommended Standards
- 2-({2'-amino-3'-cyano-6'-methyl-2-oxo-1-propyl-1,2-dihydrospiro[indole-3,4'-pyran]-5'-yl}carbonyloxy)ethyl 2-methylprop-2-enoate (CAS 939888-70-7)
- 4-Hydroxy Propranolol Glucuronide (CAS 94731-13-2)
- 1,5-Naphthalenedisulfonic acid, 3-[2-(4-amino-5-methoxy-2-methylphenyl)diazenyl]- (CAS 61827-75-6)
- 4-Hydroxypropranolol ß-Glucuronide-D6 (CAS 29858-53-5)
- Ethyl 2-(3-formyl-4-nitrophenoxy)acetate (CAS 105728-02-7)
- N-(5-Amino-2-methoxyphenyl)-2-(4-methylphenoxy)-acetamide (CAS 1016696-96-0)
- 2-Ethyl-2,3-dihydrobenzofuran-2-carbothioamide (CAS 368423-55-6)
- 2,2,2-Trichloroethyl (E)-(2-(furan-2-yl)vinyl)carbamate (CAS 338399-69-2)
- Dibenzo[b,e][1,4]dioxine-2-carboxylic acid (CAS 17054-75-0)
- 3,3-Diallyl-3lambda5-[1,1'-biphenyl]-4,4'-diol (CAS 6942-01-4)
- 3-Amino-3-cyclopropylpropan-1-ol (CAS 683220-79-3)
- Cyclopropanecarbonyl cyanide (CAS 6047-92-3)
- 5-Amino-1,3,6-trimethylpyrimidine-2,4(1H,3H)-dione (CAS 55276-24-9)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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