Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(2-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate CAS 618072-60-9
| CAS No. | 618072-60-9 |
| Molecular Formula | C24H18F2N2O5S |
| Molecular Weight | 484.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(2-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(2-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate (CAS 618072-60-9), molecular formula C24H18F2N2O5S and molecular weight 484.47 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(2-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 484.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(2-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H18F2N2O5S |
| Molecular Weight | 484.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(3-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate (CAS 618072-65-4)
- Methyl 2-(3-(3-fluoro-4-methylbenzoyl)-2-(4-fluorophenyl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate (CAS 617697-95-7)
- 9-Fluoro-11β,17-dihydroxy-16α,21-bis(methoxymethoxy)-pregna-1,4-diene-3,20-dione (CAS 2822-16-4)
- (16beta)9-fluoro-16-methyl-17,21-bis(1-oxopropoxy)-Pregna-1,4,11-triene-3,20-dione (CAS 65669-64-9)
- 4-(5-((3-(3-Fluoro-4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid (CAS 623936-17-4)
- Ethyl 2-(3-(3-fluoro-4-methylbenzoyl)-4-hydroxy-5-oxo-2-(pyridin-3-yl)-2,5-dihydro-1H-pyrrol-1-yl)-4-methylthiazole-5-carboxylate (CAS 618072-71-2)
- N-{2-[5-Fluoro-2-(pyridin-2-yl)-1H-indol-3-yl]ethyl}-4-phenoxybenzene-1-sulfonamide (CAS 1253527-96-6)
- 3-(6-Fluoro-1H-indol-3-yl)-2-(4-iodobenzenesulfonamido)propanoic acid (CAS 1796902-05-0)
Recommended Standards
- 3-[(5Z)-4-Oxo-2-sulfanylidene-5-{[2-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidin-3-yl]-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13),5,7,9,11-pentaene-2,4-dione (CAS 477859-31-7)
- Ceftolozane Impurity 33 (CAS CATO-C4X-240633)
- Cefotaxime Impurity 86 (CAS CATO-C4X-120186)
- N-(3-((4-(Bis(2-chloroethyl)amino)phenyl)thio)propyl)acridin-9-amine (CAS 130031-49-1)
- N-Succinyl-5-aminoimidazole-4-carboxamide Ribose 5-Phosphate (CAS 3031-95-6)
- 1-(4-(2-Chlorophenyl)-1H-pyrrol-3-yl)ethanone (CAS 87388-52-1)
- 2,3-Dimethylquinoxaline hydrate (CAS 1134741-00-6)
- Minodronic Acid (CAS 180064-38-4)
- 4-(Cyclopropylmethoxy)-3-ethylphenol (CAS 1243310-44-2)
- 1-(Benzo[d]oxazol-2-yl)piperidine-2-carboxylic acid (CAS 1169873-86-2)
- (E)-3-(5-bromo-2-(2-methoxy-2-oxoethoxy)phenyl)acrylic acid (CAS 937599-46-7)
- D-Asparagine (CAS 2058-58-4)
- 3-Amino-5-chloro-N,N-diethylbenzamide hydrochloride (CAS 1881290-51-2)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
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