5-(2-Chloro-6-fluorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one CAS 618076-80-5
| CAS No. | 618076-80-5 |
| Molecular Formula | C20H15ClFN3O2S |
| Molecular Weight | 415.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 415.87 g/mol gives 5-(2-Chloro-6-fluorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-(2-Chloro-6-fluorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 618076-80-5), a certified reference material (molecular formula C20H15ClFN3O2S, MW 415.87 g/mol) for analytical method development and quality control.
5-(2-Chloro-6-fluorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (C20H15ClFN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(2-Chloro-6-fluorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H15ClFN3O2S |
| Molecular Weight | 415.87 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- (Z)-3-Chloro-N,N'-bis[(thiophen-2-yl)methyl]-5-(trifluoromethyl)pyridine-2-carboximidamide (CAS 338758-27-3)
- ((4'-Chloro-[1,1'-biphenyl]-4-yl)sulfonyl)phenylalanine (CAS 1449133-06-5)
- 2-(2-Chloro-5-(phenylsulfonyl)benzamido)benzoic acid (CAS 724440-27-1)
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Recommended Standards
- Prucalopride Impurity 41（DP-4） (CAS 1900715-95-8)
- Dronedarone Impurity 23 (CAS CATO-C4X-109223)
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- Isavuconazole Impurity 32 (CAS 338990-31-1)
- 3-Amino-4-methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester (CAS 114214-52-7)
- Ethyl 4-ethoxy-4-iminobutanoate hydrochloride (CAS 90205-55-3)
- 1-(1h-Indol-7-yl)ethan-1-one (CAS 104019-20-7)
- 8-(2,2,2-Trifluoroethyl)-1,4-dioxa-8-azaspiro[4.5]Decane (CAS 710350-66-6)
- 4-(Difluoromethyl)-2,3-dimethylpyridine (CAS 1804753-74-9)
- N-(2-methylpropyl)-3-(trifluoromethyl)aniline hydrochloride (CAS 1909347-96-1)
- 2-(2-(1H-Imidazol-1-yl)ethyl)piperidine (CAS 278789-09-6)
- n-(1-Benzyl-4-cyanopiperidin-4-yl)-2,2,2-trifluoroacetamide, trifluoroacetic acid (CAS 1432682-00-2)
- 3-(3,4-dimethoxyphenyl)-2-methylpropanenitrile (CAS 1461705-74-7)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
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