1-(3-Chlorophenyl)-3-(p-tolyl)-1H-pyrazol-5-amine CAS 618098-27-4
| CAS No. | 618098-27-4 |
| Molecular Formula | C16H14ClN3 |
| Molecular Weight | 283.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 1-(3-Chlorophenyl)-3-(p-tolyl)-1H-pyrazol-5-amine (CAS 618098-27-4), a certified reference material (molecular formula C16H14ClN3, MW 283.76 g/mol) for analytical method development and quality control.
1-(3-Chlorophenyl)-3-(p-tolyl)-1H-pyrazol-5-amine (C16H14ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H14ClN3 |
| Molecular Weight | 283.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 1-benzyl-3-(3-chlorophenyl)-1H-pyrazol-5-amine (CAS 1154569-19-3)
- 1-(4-Chlorophenyl)-4-p-tolyl-1H-pyrazol-5-amine (CAS 1202029-96-6)
- 1-(3-Chlorophenyl)-3-(m-tolyl)-1H-pyrazol-5-amine (CAS 618098-32-1)
- 1-(3-Chlorophenyl)-3-(o-tolyl)-1H-pyrazol-5-amine (CAS 618098-33-2)
- 1-(3-Chlorophenyl)-4-(2-methylphenyl)-1H-pyrazol-5-amine (CAS 324009-02-1)
- 1-(3-Chlorophenyl)-4-(m-tolyl)-1H-pyrazol-5-amine (CAS 242797-15-5)
- 1-(3-Chlorophenyl)-4-(p-tolyl)-1H-pyrazol-5-amine (CAS 242797-19-9)
- 1-(4-Chlorophenyl)-3-(m-tolyl)-1H-pyrazol-5-amine (CAS 618092-76-5)
Recommended Standards
- 2-Chloro-6-methyl-4-phenyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 1708401-43-7)
- 3-Chloro-7-methyl-1-phenyl-5,6,7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile (CAS 1447960-16-8)
- N-benzyl-2-chloro-N-methylquinazolin-4-amine (CAS 144511-92-2)
- 1-(4-Chlorophenyl)-3-(o-tolyl)-1H-pyrazol-5-amine (CAS 618092-78-7)
- tert-Butyl 6-amino-3-((diethylamino)methyl)-1H-indazole-1-carboxylate (CAS 887590-89-8)
- 4-Methyl-3-(pentyloxy)benzenethiol (CAS 1379367-30-2)
- 2-(8-Ethoxyoctyl)-5-hexylfuran (CAS 88646-98-4)
- Drotaverin Impurity 78 (CAS CATO-C4X-243578)
- 2-Allyl-4-methylbenzo[b]thiophene (CAS 89816-54-6)
- (S)-3-Amino-1-hexanol Hydrochloride (CAS 68889-62-3)
- 2,3,3',4,5',6-Hexachlorobiphenyl (CAS 74472-43-8)
- 6-Fluoro-7-methylchroman-2-carboxylic acid (CAS 1420790-16-4)
- 7-Chloro-4-(3-ethoxybenzyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one (CAS 1326893-85-9)
- (Des-Thr7)-Glucagon trifluoroacetate salt (CAS 1802078-28-9)
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