3-(4-Bromophenyl)-1-(2-fluorophenyl)-1H-pyrazole-4-carbaldehyde CAS 618098-71-8

Purity 97%+In StockPharmaceutical Standards
CAS No.618098-71-8
Molecular FormulaC16H10BrFN2O
Molecular Weight345.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Bromophenyl)-1-(2-fluorophenyl)-1H-pyrazole-4-carbaldehyde CAS 618098-71-8 chemical structure

Description

The molecular framework of 3-(4-Bromophenyl)-1-(2-fluorophenyl)-1H-pyrazole-4-carbaldehyde (C16H10BrFN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

3-(4-Bromophenyl)-1-(2-fluorophenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-71-8), molecular formula C16H10BrFN2O and molecular weight 345.17 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(4-Bromophenyl)-1-(2-fluorophenyl)-1H-pyrazole-4-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H10BrFN2O
Molecular Weight345.17 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF/Br-containing
Nitrogen Atoms2

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