1-(3-Chlorophenyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid CAS 618102-47-9
| CAS No. | 618102-47-9 |
| Molecular Formula | C16H10Cl2N2O2 |
| Molecular Weight | 333.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(3-Chlorophenyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(3-Chlorophenyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-47-9), molecular formula C16H10Cl2N2O2 and molecular weight 333.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-Chlorophenyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid (C16H10Cl2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10Cl2N2O2 |
| Molecular Weight | 333.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- (4Z)-4-{[(4-chlorophenyl)amino]methylidene}-1-(6-chloropyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one (CAS 320419-11-2)
- 1-(2-Chlorophenyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-53-7)
- 1-(3-Chlorophenyl)-5-(4-chlorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 477711-99-2)
- 1,3-Bis(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-37-7)
- 1,5-Bis(4-chlorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 477712-01-9)
- 3-(2-Chlorophenyl)-N-(3-chlorophenyl)isoxazole-5-carboxamide (CAS 477859-16-8)
- 5-(2-Chlorophenyl)-1-(3-chlorophenyl)-1H-pyrazole-3-carboxylic acid (CAS 477712-04-2)
- (3-Chlorophenyl)(3-(4-chlorophenyl)-5,6-dihydropyridazin-1(4H)-yl)methanone (CAS 159799-55-0)
Recommended Standards
- 1-(2,4-Dichlorophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid (CAS 477712-39-3)
- (R)-O-(2,5-Dichlorophenyl) O-methyl phenylphosphonothioate (CAS 73306-98-6)
- 1-[(2,4-Dichlorophenyl)amino]-3-phenyl-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 271254-72-9)
- (3-Iodo-benzyl)-carbamic acid tert-butyl ester (CAS 263351-43-5)
- α-Cyclogeraniol (CAS 6627-74-3)
- Bendamustine Amino Isopropyl Ester Impurity (CAS 1313020-26-6)
- 6-Ethynylpyridazin-3-amine (CAS 1710472-52-8)
- 2-Amino-N-(1,1-dioxidotetrahydrothiophen-3-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 618077-54-6)
- Ibrutinib Impurity 157 (CAS CATO-C4X-1064157)
- 2-(3-(Trifluoromethyl)-1h-pyrazol-1-yl)acetonitrile (CAS 1006348-71-5)
- N-(2-Methoxybenzyl)-1,5-dimethyl-1H-pyrazol-3-amine hydrochloride (CAS 1856023-14-7)
- 1-(Bromomethyl)-2-chloro-3-iodobenzene (CAS 1261671-09-3)
- 2-Bromo-2-methyl-N-phenylpropanamide (CAS 2322-45-4)
- Semaglutide impurity 89 (CAS CATO-C4X-222689)
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