3-(4-Fluorophenyl)-1-(o-tolyl)-1H-pyrazole-5-carboxylic acid CAS 618102-79-7
| CAS No. | 618102-79-7 |
| Molecular Formula | C17H13FN2O2 |
| Molecular Weight | 296.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Fluorophenyl)-1-(o-tolyl)-1H-pyrazole-5-carboxylic acid.
3-(4-Fluorophenyl)-1-(o-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-79-7) is a high-purity analytical reference standard with the molecular formula C17H13FN2O2 and a molecular weight of 296.30 g/mol.
3-(4-Fluorophenyl)-1-(o-tolyl)-1H-pyrazole-5-carboxylic acid (C17H13FN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-Fluorophenyl)-1-(o-tolyl)-1H-pyrazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H13FN2O2 |
| Molecular Weight | 296.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 1-Benzyl-4-(3-fluorophenyl)-1,4-dihydropyrazine-2,3-dione (CAS 1226457-93-7)
- (4-Fluorophenyl)(2-(4-methoxyphenyl)-1H-imidazol-4-yl)methanone (CAS 1253697-49-2)
- Ethyl 4-(4-fluorophenyl)-1,7-naphthyridine-2-carboxylate (CAS 1956307-15-5)
- 1-(2-Fluorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-72-9)
- 1-(2-Fluorophenyl)-3-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-27-5)
- 1-(4-Fluorophenyl)-3-(3-methoxyphenyl)-1h-pyrazole-4-carbaldehyde (CAS 956984-87-5)
- 1-(4-Fluorophenyl)-3-(3-methylphenyl)-1h-pyrazole-4-carboxylic acid (CAS 956181-48-9)
- 1-(4-Fluorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 618098-60-5)
Recommended Standards
- 3-(4-Fluoro-benzoyl)-2-methyl-indolizine-1-carbaldehyde oxime (CAS 454447-55-3)
- 3-(4-Fluorophenyl)-1-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-73-1)
- 3-(2-(4-Fluorophenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727652-37-1)
- 3-(4-Fluorophenyl)-1-m-tolyl-1h-pyrazole-5-carboxylic acid (CAS 618102-87-7)
- 6-(Hydroxymethyl)pyridine-2-carbonitrile (CAS 50501-38-7)
- 2-(6-Amino-5-bromo-3-(difluoromethyl)pyridin-2-yl)acetic acid (CAS 1806059-37-9)
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