2-((2-(2-Chlorophenyl)-2-oxoethyl)thio)-3-(p-tolyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one CAS 618432-24-9
| CAS No. | 618432-24-9 |
| Molecular Formula | C25H21ClN2O2S2 |
| Molecular Weight | 481.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((2-(2-Chlorophenyl)-2-oxoethyl)thio)-3-(p-tolyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one.
CATO supplies 2-((2-(2-Chlorophenyl)-2-oxoethyl)thio)-3-(p-tolyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 618432-24-9), a certified reference material (molecular formula C25H21ClN2O2S2, MW 481.03 g/mol) for analytical method development and quality control.
The molecular framework of 2-((2-(2-Chlorophenyl)-2-oxoethyl)thio)-3-(p-tolyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (C25H21ClN2O2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-((2-(2-Chlorophenyl)-2-oxoethyl)thio)-3-(p-tolyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H21ClN2O2S2 |
| Molecular Weight | 481.03 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-2-((2-oxo-2-(p-tolyl)ethyl)thio)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 445220-56-4)
- 4-((4-Chlorophenyl)((1-(1-phenylcyclobutyl)ethylidene)hydrazono)methyl)phenyl methanesulfonate (CAS 78929-83-6)
- 2-((5-(3-Chlorophenyl)-4-(4-fluorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-isopropylphenyl)acetamide (CAS 868255-48-5)
- N-(4-Chlorophenyl)-2-((5-((4-methoxyphenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332912-62-6)
- 4-(4-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 303984-65-8)
- 3-((4-Chlorophenyl)sulfonyl)-1-(furan-2-ylmethyl)-2-imino-8-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606953-66-6)
- 3-Chlorophenyl-4'-nitrophenyl ether (CAS 2303-23-3)
- 1022065-74-2 1,3-Bis(4-chlorophenyl)-5-((4-ethoxyphenyl)methylene)-1,3-diazaperhydroine-2,4,6-trione MFCD04154225 (CAS 1022065-74-2)
Recommended Standards
- 6-Bromo-4-(dibromomethyl)-5,5-dimethyl-N-(pyridin-2-yl)bicyclo[2.1.1]Hexane-1-carboxamide (CAS 256954-40-2)
- 3,5-Diiodothyronamine (CAS 3687-09-0)
- N-(3-((5-Chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)thio)phenyl)acrylamide (CAS 1214265-57-2)
- 2-(2,4-Dichlorobenzoyl)-3-(2,4-dichlorophenoxy)-5-(trifluoromethyl)pyridine (CAS 306977-37-7)
- 2-(4-Fluoro-3-methylphenyl)morpholine (CAS 1267436-33-8)
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- 5-Amino-1-(1-phenylpiperidin-4-yl)-1H-pyrazol-3-ol (CAS 955962-96-6)
- 6-(Chloromethyl)-N-(2,3-dichlorophenyl)-1,3,5-triazine-2,4-diamine (CAS 1379811-51-4)
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