(3-(2,4-Dichloro-5-fluorophenyl)-1-(o-tolyl)-1H-pyrazol-4-yl)methanol CAS 618441-85-3
| CAS No. | 618441-85-3 |
| Molecular Formula | C17H13Cl2FN2O |
| Molecular Weight | 351.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(3-(2,4-Dichloro-5-fluorophenyl)-1-(o-tolyl)-1H-pyrazol-4-yl)methanol (CAS 618441-85-3), molecular formula C17H13Cl2FN2O and molecular weight 351.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3-(2,4-Dichloro-5-fluorophenyl)-1-(o-tolyl)-1H-pyrazol-4-yl)methanol (C17H13Cl2FN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H13Cl2FN2O |
| Molecular Weight | 351.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- (3-(2,4-Dichloro-5-fluorophenyl)-1-(m-tolyl)-1H-pyrazol-4-yl)methanol (CAS 618441-90-0)
- 3,3-DIchloro-5-(morpholin-4-ylsulfonyl)-1,3-dihydro-2h-indol-2-one (CAS 220428-21-7)
- 5,7-Dichloro-3,4-diphenylcinnoline (CAS 1240594-32-4)
- 2,4-Dichloro-N-(4-morpholinophenyl)benzamide (CAS 250714-46-6)
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- 3-(2,4-Dichloro-5-fluorophenyl)-1-phenyl-1H-pyrazole-5-carboxylic acid (CAS 618382-91-5)
- 2,2-Dichloro-N-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl)acetamide (CAS 349616-50-8)
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