(1-(3-Chloro-4-fluorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazol-4-yl)methanol CAS 618444-59-0
| CAS No. | 618444-59-0 |
| Molecular Formula | C18H14ClFN2O3 |
| Molecular Weight | 360.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (1-(3-Chloro-4-fluorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazol-4-yl)methanol (CAS 618444-59-0), a certified reference material (molecular formula C18H14ClFN2O3, MW 360.77 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (1-(3-Chloro-4-fluorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazol-4-yl)methanol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (1-(3-Chloro-4-fluorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1H-pyrazol-4-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14ClFN2O3 |
| Molecular Weight | 360.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-6-fluorobenzyl 3-(5-phenyl-1,3,4-oxadiazol-2-yl)propanoate (CAS 869718-32-1)
- N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}ethyl)benzamide (CAS 1043330-64-8)
- N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}phenyl)propanamide (CAS 338407-17-3)
- 1-(5-Chloro-2,4-dimethoxyphenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1351835-96-5)
- 2-[2-(4-Chloro-2-nitrophenyl)diazenyl]-3-oxo-N-phenylbutanamide (CAS 4106-76-7)
- 8-Chloro-1-(2,6-difluorophenyl)-4-((dimethylamino)methylene)-3H-benzo[c]azepin-5(4H)-one (CAS 869366-10-9)
- Ethyl 2-((6-chloro-2-(4-methoxyphenyl)-1H-benzo[d]imidazol-1-yl)oxy)acetate (CAS 338978-97-5)
- 4-Chloro-1-(phenylsulfonyl)-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1196507-57-9)
Recommended Standards
- 2-[(1R,2R)-2-benzyloxy-1-methyl-propoxy]-4-chloro-5-(trifluoromethyl)pyrimidine (CAS 2306253-24-5)
- 2'-(Chloromethyl)-4-fluoro-2-methoxy-5-(1-methylethyl)-4'-(trifluoromethyl)-1,1'-biphenyl (CAS 875551-28-3)
- 4-[(1R,2R)-2-Benzyloxy-1-methyl-propoxy]-2-chloro-5-(trifluoromethyl)pyrimidine (CAS 1223498-50-7)
- N-(6-amino-7-methoxyquinazolin-4-yl)-N-(3-chloro-4-fluorophenyl)acetamide (CAS 869199-62-2)
- N'-(3-(3,4-dimethylphenyl)-4-oxo-3,4-dihydrophthalazine-1-carbonyl)-4-methylbenzenesulfonohydrazide (CAS 866039-07-8)
- 3-(Piperazine-1-carbonyl)-1lambda6-thiolane-1,1-dione hydrochloride (CAS 1049765-76-5)
- 4-(3-Bromo-2-(trifluoromethyl)phenyl)morpholine (CAS 1779127-84-2)
- Thiotepa Impurity 4 (CAS CATO-C4X-21564)
- 3-((4-Bromophenyl)thio)-1-(4-hydroxyphenyl)propan-1-one (CAS 882748-46-1)
- tetramethyl-1,4-dioxane-2,6-dione (CAS 58607-24-2)
- 0359AD 1185299-39-1 3-(2-Ethylphenoxy)pyrrolidine hydrochloride C12H18ClNO (CAS 1185299-39-1)
- 4-(4-Chlorobenzenesulfonyl)-1h-pyrazol-5-amine (CAS 30036-43-2)
- Ethyl 2-amino-5-(isopropylcarbamoyl)-4-methylthiophene-3-carboxylate (CAS 886672-89-5)
- (D-Ala2)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 444073-04-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com