1-acetyl-1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile CAS 618446-36-9
| CAS No. | 618446-36-9 |
| Molecular Formula | C10H7N3O |
| Molecular Weight | 185.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-acetyl-1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile (C10H7N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-acetyl-1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 618446-36-9) is a high-purity analytical reference standard with the molecular formula C10H7N3O and a molecular weight of 185.18 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-acetyl-1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7N3O |
| Molecular Weight | 185.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
Recommended Standards
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- 6-Isopropyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-amine (CAS 1355233-44-1)
- (E)-[1-(2,4-Dimethyl-1,3-thiazol-5-yl)ethylidene]amino 4-fluorobenzoate (CAS 477872-41-6)
- 3-(2-Chloro-6-fluorophenyl)-4-(4-fluorobenzoyl)-1-methylpyrrolidine (CAS 478043-70-8)
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