5,6-Dichloro-2-methylquinolin-8-amine CAS 61854-66-8
| CAS No. | 61854-66-8 |
| Molecular Formula | C10H8Cl2N2 |
| Molecular Weight | 227.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5,6-Dichloro-2-methylquinolin-8-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5,6-Dichloro-2-methylquinolin-8-amine (CAS 61854-66-8) is a high-purity analytical reference standard with the molecular formula C10H8Cl2N2 and a molecular weight of 227.09 g/mol.
5,6-Dichloro-2-methylquinolin-8-amine (C10H8Cl2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8Cl2N2 |
| Molecular Weight | 227.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 1-Benzyl-4,5-dichloro-1H-imidazole (CAS 107108-24-7)
- 2,8-Dichloro-6-methylquinolin-5-amine (CAS 1071675-48-3)
- methyl 3,6-dichloro-5-methylpyridazine-4-carboxylate (CAS 1363381-53-6)
- 2,4-Dichloro-8-methylquinolin-3-amine (CAS 1447960-14-6)
- 2,5-Dichloro-4-(1H-pyrrol-1-yl)aniline (CAS 175135-55-4)
- 1,3-Dichloro-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 4695-92-5)
- 2,3-Dichloro-6,7-dimethylquinoxaline (CAS 63810-80-0)
- 2,4-Dichloro-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 2768870-78-4)
Recommended Standards
- 4-Amino-6,8-dichloro-2-methylquinoline (CAS 917562-01-7)
- 5,7-Dichloro-2-methylquinolin-4-amine (CAS 917562-03-9)
- 4,8-Dichloro-2-ethylquinazoline (CAS 887592-05-4)
- 5-Chloro-3-(4-chlorophenyl)-1-methyl-1H-pyrazole (CAS 524740-38-3)
- Di-μ-chlorodimethylbis(triphenylphosphine)dipalladium (CAS 149869-56-7)
- 1,3,5-Tris(carboxymethyl)benzene 4435-67-0 Benzene-1,3,5-triacetic acid (CAS 4435-67-0)
- 2-Phenyl-1H-imidazole-4,5-dicarboxylic acid (CAS 888-60-8)
- 2-(Thiomorpholine-4-carbonyl)aniline (CAS 664303-98-4)
- 8-Ethyl-3-hydrazinyl-5H-[1,2,4]triazino[5,6-b]indole (CAS 420102-20-1)
- Iron(II) trifluoromethanesulfonate 59163-91-6 IRON TRIFLATE;IRON(II) TRIFLATE;IRON(II) TRIFLUOROMETHANESULFONATE SC10847 (CAS 59163-91-6)
- Landiolol Impurity 35 (CAS CATO-C4X-262135)
- 2-(1-Hydroxyethyl)quinolin-8-ol (CAS 873399-69-0)
- (Z)-4-Oxo-4-((4-(N-(thiazol-2-yl)sulfamoyl)phenyl)amino)but-2-enoic acid (CAS 515-57-1)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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