(2S)-1-(4-chlorophenyl)pyrrolidine-2-carboxylic acid CAS 61898-80-4

Purity 97%+In StockPharmaceutical Standards
CAS No.61898-80-4
Molecular FormulaC11H18ClNO2
Molecular Weight231.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2S)-1-(4-chlorophenyl)pyrrolidine-2-carboxylic acid CAS 61898-80-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2S)-1-(4-chlorophenyl)pyrrolidine-2-carboxylic acid.

CATO supplies (2S)-1-(4-chlorophenyl)pyrrolidine-2-carboxylic acid (CAS 61898-80-4), a certified reference material (molecular formula C11H18ClNO2, MW 231.72 g/mol) for analytical method development and quality control.

The molecular framework of (2S)-1-(4-chlorophenyl)pyrrolidine-2-carboxylic acid (C11H18ClNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures (2S)-1-(4-chlorophenyl)pyrrolidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H18ClNO2
Molecular Weight231.72 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1974
Halogen ContentCl-containing
Nitrogen Atoms1

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