1-(2-Hydroxypropyl)-5-methylpyrimidine-2,4(1H,3H)-dione CAS 62009-50-1
| CAS No. | 62009-50-1 |
| Molecular Formula | C8H12N2O3 |
| Molecular Weight | 184.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2-Hydroxypropyl)-5-methylpyrimidine-2,4(1H,3H)-dione is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(2-Hydroxypropyl)-5-methylpyrimidine-2,4(1H,3H)-dione (CAS 62009-50-1), molecular formula C8H12N2O3 and molecular weight 184.19 g/mol, is a CATO reference standard with documented purity and traceability.
1-(2-Hydroxypropyl)-5-methylpyrimidine-2,4(1H,3H)-dione (C8H12N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O3 |
| Molecular Weight | 184.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
Related Hydroxypropyl Standards
- 2-(4-(3-Hydroxypropyl)-1H-pyrazol-1-yl)acetic acid (CAS 1172859-19-6)
- 2-(1-Hydroxypropyl)-5-methyloxazole-4-carboxamide (CAS 61183-23-1)
- Methyl 5-(3-hydroxypropyl)furan-2-carboxylate (CAS 2170267-71-5)
- 8-(3-Hydroxypropyl)-8-azabicyclo[3.2.1]Octan-3-one (CAS 103323-43-9)
- Methyl 2-(3-hydroxypropyl)oxazole-4-carboxylate (CAS 1355026-81-1)
- 2-(3-Hydroxypropyl)-5-methoxyphenol (CAS 106800-26-4)
- 4-(3-Hydroxypropyl)-3-methoxyphenol (CAS 106800-27-5)
- 2-(3-Hydroxypropyl)-6-methoxyphenol (CAS 106800-28-6)
Recommended Standards
- 1-(1-Hydroxy-2-methylpropan-2-yl)-1H-pyrazole-4-carboxylic acid (CAS 2306277-32-5)
- 1-(2-Methoxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid (CAS 864522-54-3)
- [2,4'-Bipyridine]-5-carbaldehyde (CAS 834881-87-7)
- 1-(3,4-Dimethoxy-5-methylfuran-2-yl)ethanone (CAS 93965-68-5)
- N,N'-Bis(2,4-difluorophenyl)urea (CAS 1581-06-2)
- 6-aminonaphthalene-1-carbonitrile (CAS 91135-41-0)
- (4-(Tert-butyl)phenyl)(3-fluorophenyl)methanol (CAS 844683-59-6)
- Cefmetazole Impurity 55 (CAS CATO-C4X-150755)
- 7-Cyclopropyl-2,7-diazaspiro[3.5]nonane (dihydrochloride) (CAS 1415562-71-8)
- 3-Methyl-1H-pyrrolo[3,2-b]pyridin-5-ol (CAS 1190311-86-4)
- 1-(4-Methoxyphenyl)-3-methyl-1H-indole (CAS 876337-56-3)
- 2-amino-N-(2-fluoroethyl)propanamide hydrochloride (CAS 1803560-80-6)
- 2-(4-Fluorophenyl)-1-(4-methoxyphenyl)Ethylamine (CAS 170688-03-6)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
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