2-(1H-1,2,4-Triazol-5-yl)aniline CAS 6219-58-5
| CAS No. | 6219-58-5 |
| Molecular Formula | C8H8N4 |
| Molecular Weight | 160.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(1H-1,2,4-Triazol-5-yl)aniline (CAS 6219-58-5), molecular formula C8H8N4 and molecular weight 160.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(1H-1,2,4-Triazol-5-yl)aniline (C8H8N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8N4 |
| Molecular Weight | 160.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 4 |
Related H Standards
- 2-(2H-1,2,3-Triazol-2-yl)aniline (CAS 1173462-33-3)
- 2-(1H-1,2,3-triazol-1-yl)aniline (CAS 15213-01-1)
- 3-(1H-1,2,3-Triazol-1-yl)aniline (CAS 16279-73-5)
- 4-(Triazol-1-yl)aniline (CAS 16279-88-2)
- 3-(1,2,4-Triazol-1-yl)aniline (CAS 176032-78-3)
- 2-(1,2,4-Triazol-1-yl)aniline (CAS 39876-84-1)
- 2-(4h-1,2,4-Triazol-4-yl)aniline (CAS 25660-59-7)
- 3-(2H-1,2,3-triazol-2-yl)aniline, 97% (CAS 626248-56-4)
Recommended Standards
- 2-(1h-Imidazol-1-yl)pyridin-4-amine (CAS 262295-99-8)
- 2-((1-Methyl-1H-imidazol-5-yl)methyl)malononitrile (CAS 771550-81-3)
- 2-(1H-Imidazol-2-yl)pyridin-3-amine (CAS 88128-92-1)
- 1-Phenyl-1H-1,2,4-triazol-5-amine (CAS 68207-62-5)
- 5-Bromo-1-naphthohydrazide (CAS 22531-60-8)
- 2-[(propan-2-yl)amino]pyridine-3-carboxylic acid (CAS 885275-12-7)
- 8BT63DA42E 325715-02-4 Indiplon [USAN:INN] Indiplon Acetamide, N-methyl-N-(3-(3-(2-thienylcarbonyl)pyrazolo(1,5-a)pyrimidin-7-yl)phenyl)- NBI 34060 3-(2-Thienylcarbonyl)-7-(3-N-methylacetamide)-pyrazolo(1,5-alpha)pyrimidine N-Methyl-N-(3-3-(thiophen-2-ylcarbonyl)pyrazolo(1,5-a)pyrimidin-7-yl)phenyl)acetamide N-Methyl-N-(3-(3-(2-thienylcarbonyl)-pyrazolo(1,5-a)pyrimidin-7-yl)phenyl)acetamide UNII-8BT63DA42E NBI-34060 (CAS 325715-02-4)
- (1S,2S)-1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 888407-46-3)
- 4-Amino-2-methyl-1H-isoindole-1,3(2H)-dione (CAS 2257-85-4)
- 3,3-Dimethyl-2-piperazinone (CAS 22476-74-0)
- 1-(4-Bromo-3-fluorophenyl)piperidin-4-one (CAS 1492496-42-0)
- N1-Isobutyl-4-methylbenzene-1,2-diamine (CAS 649763-41-7)
- 2-Bromo-5-(piperazin-1-yl)pyrazine (CAS 446286-90-4)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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