6-Chlorothieno[2,3-b]pyridine CAS 62226-18-0
| CAS No. | 62226-18-0 |
| Molecular Formula | C7H4ClNS |
| Molecular Weight | 169.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chlorothieno[2,3-b]pyridine (CAS 62226-18-0) is a high-purity analytical reference standard with the molecular formula C7H4ClNS and a molecular weight of 169.63 g/mol.
The molecular framework of 6-Chlorothieno[2,3-b]pyridine (C7H4ClNS) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4ClNS |
| Molecular Weight | 169.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorothieno Standards
- 6-Chlorothieno[3,2-c]pyridine (CAS 1781989-24-9)
- 2-Chlorothieno[2,3-b]pyridine (CAS 1823943-95-8)
- 2-Chlorothieno[2,3-c]pyridine (CAS 756477-32-4)
- 2-Chlorothieno[3,2-b]pyridine (CAS 94191-14-7)
- 2-Chlorothieno[3,2-c]pyridine (CAS 28783-23-5)
- 3-Chlorothieno[2,3-b]pyridine (CAS 53399-36-3)
- 3-Chlorothieno[3,2-b]pyridine (CAS 94191-11-4)
- 4-Chlorothieno[2,3-c]pyridine (CAS 477874-92-3)
Recommended Standards
- 6-Chlorobenzo[d]thiazole (CAS 2942-10-1)
- 7-Chlorobenzo[d]isothiazole (CAS 89583-90-4)
- 6-Chlorobenzo[d]isothiazole (CAS 89583-89-1)
- 7-Chlorobenzo[d]thiazole (CAS 2942-09-8)
- n-(Cyclopropylmethyl)-2,5-dimethylaniline (CAS 356539-50-9)
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- 2,7-Diamino-2-phenylheptanoic acid dihydrochloride (CAS 1177328-53-8)
- 1-Benzyl 2-methyl 4-(2-aminoethyl)piperazine-1,2-dicarboxylate (CAS 1353943-42-6)
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