4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(2-(1-methylpiperidin-4-yl)ethoxy)quinoline-3-carbonitrile CAS 622368-88-1
| CAS No. | 622368-88-1 |
| Molecular Formula | C26H28Cl2N4O3 |
| Molecular Weight | 515.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(2-(1-methylpiperidin-4-yl)ethoxy)quinoline-3-carbonitrile.
CATO supplies 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(2-(1-methylpiperidin-4-yl)ethoxy)quinoline-3-carbonitrile (CAS 622368-88-1), a certified reference material (molecular formula C26H28Cl2N4O3, MW 515.43 g/mol) for analytical method development and quality control.
Based on its molecular formula C26H28Cl2N4O3, 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(2-(1-methylpiperidin-4-yl)ethoxy)quinoline-3-carbonitrile contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 515.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(2-(1-methylpiperidin-4-yl)ethoxy)quinoline-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H28Cl2N4O3 |
| Molecular Weight | 515.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichloro Standards
- 6,7-Dichloro-1,4-bis((2,6-dimethylphenyl)amino)anthracene-9,10-dione (CAS 67906-36-9)
- 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (CAS 315224-26-1)
- 1-Benzyl-3-(3,5-dichloro-4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)imidazolidin-2-one (CAS 1092345-97-5)
- 1-(3,5-Dichloro-4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-3-[(pyridin-2-yl)methyl]imidazolidin-2-one (CAS 1092346-45-6)
- N-(2,4-dichloro-5-isopropoxyphenyl)-2-((2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethyl)sulfinyl)acetamide (CAS 341964-76-9)
- Ethyl 2-{2,4-dichloro-5-[3-(2-nitrophenoxy)thiophene-2-amido]phenoxy}acetate (CAS 339015-23-5)
- Ethyl 2-{2,4-dichloro-5-[3-(4-nitrophenoxy)thiophene-2-amido]phenoxy}acetate (CAS 339015-28-0)
- (+)-N-((2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)carbamoyl)-2,6-difluorobenzamide (CAS 130841-22-4)
Recommended Standards
- Platinum,(2-aminocyclohexanemethanamine-N,N')[D-glucuronato(2-)-O5,O6]- (CAS 70290-16-3)
- Ethyl 2-(4-bromobenzyl)-5-(4-methoxyphenyl)-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 5850-97-5)
- Propargyl-PEG9-bromide (CAS 2055042-83-4)
- Chlorodimethyl(triacontyl)silane (CAS 70851-52-4)
- 2-(4-Amino-5-methyl-1h-pyrazol-1-yl)acetic acid (CAS 1343304-07-3)
- 2-Methoxy-2-(3-pyrrolinomethyl) benzophenone (CAS 898762-85-1)
- 1,3,4-Triphenyl-1H-1,2,4-triazole-5(4H)-selenone (CAS 185761-76-6)
- 1,4-Piperidinedicarboxylic acid, 4-(2-propyn-1-yl)-, 1-(1,1-dimethylethyl) 4-ethyl ester (CAS 2022370-40-5)
- 1-[2-(Methylsulphonyl)phenyl]piperazine (CAS 313490-26-5)
- 4-Bromo-8-methylquinoline-3-carboxylic acid (CAS 1378259-81-4)
- 1-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-3-(1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl)urea (CAS 894023-11-1)
- (1R,3r)-3-(3-chlorophenyl)cyclobutan-1-amine hydrochloride (CAS 1807939-90-7)
- 7-Oxo-5-propyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 904500-44-3)
- Lixisenatide (CAS 320367-13-3（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com