1,3-Oxazole-4-carbonyl chloride CAS 62348-20-3
| CAS No. | 62348-20-3 |
| Molecular Formula | C4H2ClNO2 |
| Molecular Weight | 131.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,3-Oxazole-4-carbonyl chloride.
1,3-Oxazole-4-carbonyl chloride (CAS 62348-20-3) is a high-purity analytical reference standard with the molecular formula C4H2ClNO2 and a molecular weight of 131.52 g/mol.
1,3-Oxazole-4-carbonyl chloride (C4H2ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,3-Oxazole-4-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H2ClNO2 |
| Molecular Weight | 131.52 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Oxazole Standards
- 1,3-Oxazole-5-carbonyl chloride 118994-91-5 (CAS 118994-91-5)
- 5-methyl-1,3-oxazole-2-carboxylic acid (CAS 45676-69-5)
- 5-ethyl-1,2-oxazole-3-carbaldehyde (CAS 1368365-43-8)
- Oxazole-4-carbothioamide (CAS 118802-31-6)
- 1,2-Oxazole-5-carbothioamide (CAS 175334-72-2)
- Oxazole-5-carbothioamide (CAS 885274-32-8)
- Oxazole-5-acetic Acid (CAS 1083337-90-9)
- Methyl oxazole-4-carboxylate (CAS 170487-38-4)
Recommended Standards
- 4-Chloro-1,3,5-triazin-2-ol (CAS 168075-30-7)
- 3-Isoxazolecarbonyl chloride (CAS 53064-54-3)
- 5-Isoxazolecarboxaldehyde,3-chloro- (CAS 220780-53-0)
- 2-Chlorooxazole-4-carbaldehyde (CAS 1060816-36-5)
- Ethyl 5-chloro-5-hexenoate (CAS 485320-21-6)
- Ethyl 6-bromo-1,2,3,4-tetrahydronaphthalene-2-carboxylate (CAS 97902-66-4)
- (E)-4-(3-(3,4-dichlorophenyl)-3-oxoprop-1-en-1-yl)phenyl thiophene-2-carboxylate (CAS 329702-32-1)
- N,N'-((5-(4-Aminobutoxy)-1,3-phenylene)bis(methylene))bis(1-(pyridin-2-yl)-N-(pyridin-2-ylmethyl)methanamine) (CAS 819066-98-3)
- (5-(4-Chloro-2-fluorophenyl)pyridin-3-yl)methanamine (CAS 1346691-92-6)
- 3-(Piperidin-4-yloxy)pyridine (CAS 310881-48-2)
- 1-(2-Chlorobenzyl)-N-(2,5-dimethoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 400077-81-8)
- 2-(4-Hydroxy-2-oxoindolin-3-yl)acetonitrile (CAS 1380540-77-1)
- 2-{7,7-dimethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl}acetic acid (CAS 1421601-82-2)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
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