H-D-Pro-Phe-Arg-pNA · 2 HCl CAS 62354-56-7
| CAS No. | 62354-56-7 |
| Molecular Formula | C26H34N8O5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
H-D-Pro-Phe-Arg-pNA · 2 HCl (CAS 62354-56-7), molecular formula C26H34N8O5HCl and molecular weight 575.07 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of H-D-Pro-Phe-Arg-pNA · 2 HCl (C26H34N8O5HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), H-D-Pro-Phe-Arg-pNA · 2 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H34N8O5 2*HCl |
| Molecular Weight | 575.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Recommended Standards
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- Tert-butyl (5-(hydroxymethyl)pyridin-3-yl)carbamate (CAS 1260771-98-9)
- Ethyl 4-bromo-1H-benzo[d]imidazole-7-carboxylate (CAS 1805750-91-7)
- 2-Fluoro-4-methoxyaniline (CAS 458-52-6)
- Venlafaxine Impurity 13 (CAS CATO-C4X-143413)
- 2,3-Dibromo-4-(hydroxymethyl)-6-methoxyphenol (CAS 1940-81-4)
- PAR-4 (1-6) (mouse) (CAS 213018-42-9)
- 1-(2-Bromophenyl)-5-(trifluoromethyl)-1H-pyrazole (CAS 497833-00-8)
- [D-Phe22]Semaglutide (CAS CATO-C4X-2226222)
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