Ethyl 4-(4-chlorophenyl)-2-(furan-2-carboxamido)thiophene-3-carboxylate CAS 6240-36-4
| CAS No. | 6240-36-4 |
| Molecular Formula | C18H14ClNO4S |
| Molecular Weight | 375.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 4-(4-chlorophenyl)-2-(furan-2-carboxamido)thiophene-3-carboxylate (CAS 6240-36-4) is a high-purity analytical reference standard with the molecular formula C18H14ClNO4S and a molecular weight of 375.83 g/mol.
The molecular framework of Ethyl 4-(4-chlorophenyl)-2-(furan-2-carboxamido)thiophene-3-carboxylate (C18H14ClNO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H14ClNO4S |
| Molecular Weight | 375.83 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
- 4-Bromo-2-iodobenzyl bromide (CAS 885681-96-9)
- 4-Bromo-2-(bromomethyl)-1-iodobenzene (CAS 495414-06-7)
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- 3-Bromo-4-iodobenzyl bromide (CAS 362529-52-0)
- 2-(5-Chloro-3-methylpyridin-2-yl)ethan-1-amine (CAS 1393570-70-1)
- Ro 5-3335 (CAS 30195-30-3)
- (4S,4'S)-2,2'-Cyclohexylidenebis[4-tert-butyl-4,5-dihydrooxazole] (CAS 298693-04-6)
- N-(4-acetylphenyl)-N’-isopropylurea (CAS 72531-19-2)
- Ethyl 3-(nitromethyl)hexanoate (CAS 128013-61-6)
- 2-Chloro-4-(4-methylthiophenyl)benzoic acid (CAS 1261900-69-9)
- 1-Methyl-N-trityl-1H-pyrazol-5-amine (CAS 1956328-07-6)
- 4,4′-Phosphinicobis[benzoic acid] (CAS 96217-57-1)
- ((1R,2R)-2-(Aminomethyl)cyclopropyl)methanol (CAS 1221274-33-4)
- Cycloaspeptide D (CAS 691363-62-9)
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