3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine CAS 624734-27-6

Purity 97%+In StockPharmaceutical Standards
CAS No.624734-27-6
Molecular FormulaC9H9F3N2
Molecular Weight202.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine CAS 624734-27-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine.

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS 624734-27-6) is a high-purity analytical reference standard with the molecular formula C9H9F3N2 and a molecular weight of 202.18 g/mol.

The molecular framework of 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine (C9H9F3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H9F3N2
Molecular Weight202.18 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF-containing
Nitrogen Atoms2

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