Methyl 2,5-dichloroquinoline-4-carboxylate CAS 62482-34-2
| CAS No. | 62482-34-2 |
| Molecular Formula | C11H7Cl2NO2 |
| Molecular Weight | 256.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Methyl 2,5-dichloroquinoline-4-carboxylate (C11H7Cl2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Methyl 2,5-dichloroquinoline-4-carboxylate (CAS 62482-34-2), molecular formula C11H7Cl2NO2 and molecular weight 256.08 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7Cl2NO2 |
| Molecular Weight | 256.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 4,8-dichloroquinoline-2-carboxylate (CAS 1020101-15-8)
- Methyl 2,4-dichloroquinoline-6-carboxylate (CAS 1260676-14-9)
- Methyl 4,7-dichloroquinoline-3-carboxylate (CAS 1448259-18-4)
- Methyl 2,4-dichloroquinoline-7-carboxylate (CAS 2095162-11-9)
- Methyl 4,6-dichloroquinoline-2-carboxylate (CAS 848501-96-2)
- Methyl 4,7-dichloroquinoline-2-carboxylate (CAS 643044-04-6)
- 2,8-Dichloroquinoline-3-carboxylic acid (CAS 1017172-90-5)
- 2,6-Dichloroquinoline-3-carboxylic acid (CAS 1017378-98-1)
Recommended Standards
- Methyl (E)-2-cyano-3-(2,4-dichlorophenyl)acrylate (CAS 681442-12-6)
- Iodomethyl 2-ethylbutanoate (CAS 83141-96-2)
- N-(2,4-Dichlorophenyl)furan-2-carboxamide (CAS 58050-54-7)
- Ethyl 5-iodopentanoate (CAS 41302-32-3)
- 3-(Methylthio)-2,5-diphenylbenzofuran (CAS 925886-01-7)
- Nebivolol-D6 (CAS 99200-09-6 (unlabeled))
- 2-(2-Bromoacetyl)-6,7-dimethylbenzofuran-5-yl acetate (CAS 581807-34-3)
- 2-(4-Ethynyl-1H-pyrazol-1-yl)acetic acid (CAS 1354706-46-9)
- Benzyl 2-amino-7-azaspiro[3.5]nonane-7-carboxylate hydrochloride (CAS 1956370-64-1)
- 8-(Methylthio)-1H-purine (CAS 33426-53-8)
- 2-Amino-N-(2-((3-(methylthio)phenyl)amino)-2-oxoethyl)acetamide hydrochloride (CAS 1833698-65-9)
- Polaprezinc Impurity 21 (CAS CATO-C4X-182121)
- N-(2-Hydroxypropyl)methacrylamide (CAS 21442-01-3)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com