5,6,7,8-Tetrahydro-3H-isochromen-3-one CAS 6249-20-3
| CAS No. | 6249-20-3 |
| Molecular Formula | C9H10O2 |
| Molecular Weight | 150.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5,6,7,8-Tetrahydro-3H-isochromen-3-one (CAS 6249-20-3), molecular formula C9H10O2 and molecular weight 150.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5,6,7,8-Tetrahydro-3H-isochromen-3-one (C9H10O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H10O2 |
| Molecular Weight | 150.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Tetrahydro Standards
- 5,6,7,8-Tetrahydro-2H-chromen-2-one (CAS 16326-65-1)
- 5,6,7,8-Tetrahydro-4H-cyclohepta[b]furan-4-one (CAS 41043-06-5)
- 5,6,7,8-Tetrahydro-2,6-naphthyridin-1(2H)-one (CAS 1170830-85-9)
- 5,6,7,8-Tetrahydro-1,7-naphthyridin-2(1H)-one (CAS 1196154-84-3)
- 5,6,7,8-Tetrahydro-1,7-naphthyridin-4-ol (CAS 1260663-31-7)
- 4,5,6,7-Tetrahydro-1h-1,3-benzodiazole-2-carbaldehyde (CAS 1342459-07-7)
- 1,2,3,4-Tetrahydro-1,8-naphthyridin-4-ol (CAS 1379218-50-4)
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Recommended Standards
- 5-(2-Methylcyclopropyl)furan-2-carbaldehyde, mixture of diastereomers (CAS 39763-79-6)
- 4-Methoxystyrene Oxide (CAS 6388-72-3)
- 5-Ethenyl-2-methoxyphenol (CAS 621-58-9)
- 4-Methoxy-2-methylbenzaldehyde (CAS 52289-54-0)
- 5-Fluorobenzo[d]isothiazole (CAS 139037-02-8)
- Bis(2-hydroxyethyl)dimethylammonium (chloride) (CAS 38402-02-7)
- 2-Methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one (CAS 1427503-36-3)
- Ethyl 6-(difluoromethyl)nicotinate (CAS 1574401-80-1)
- Isopropyl 1-methyl-1H-pyrazole-4-sulfonate (CAS CATO-C3D-2473)
- 7-Methoxy-1,2,3,4-tetrahydroacridin-9-amine (CAS 5778-80-3)
- (3,3-Diethoxypropyl)diethylamine (CAS 3616-60-2)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
- Tegoprazan Impurity 27 (CAS CATO-C4X-229727)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
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