1-Chloro-2-methoxy-5-methyl-4-nitrobenzene CAS 62492-41-5
| CAS No. | 62492-41-5 |
| Molecular Formula | C8H8ClNO3 |
| Molecular Weight | 201.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 201.61 g/mol gives 1-Chloro-2-methoxy-5-methyl-4-nitrobenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-Chloro-2-methoxy-5-methyl-4-nitrobenzene (CAS 62492-41-5) is a high-purity analytical reference standard with the molecular formula C8H8ClNO3 and a molecular weight of 201.61 g/mol.
The molecular framework of 1-Chloro-2-methoxy-5-methyl-4-nitrobenzene (C8H8ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO3 |
| Molecular Weight | 201.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 1-chloro-5-methoxy-2-methyl-4-nitrobenzene (CAS 100777-46-6)
- 1-Chloro-4-methoxy-2-methyl-5-nitrobenzene (CAS 101080-03-9)
- 1-Chloro-2-(methoxymethyl)-4-nitrobenzene (CAS 101513-52-4)
- 2-Chloro-4-(ethylamino)pyrimidine-5-carboxylic acid (CAS 101683-59-4)
- 3-Chloro-6-ethoxypyridine-2-carboxylic acid (CAS 1020945-92-9)
- 1-Chloro-2-ethoxy-4-nitrobenzene (CAS 102236-22-6)
- 2-(2-Chloro-6-nitrophenyl)ethan-1-ol (CAS 102493-68-5)
- 2-Chloro-N-(2,5-dihydroxy-phenyl)-acetamide (CAS 102580-34-7)
Recommended Standards
- 1-(Chloromethyl)-3-methoxy-2-nitrobenzene (CAS 53055-06-4)
- 1-Chloro-3-ethoxy-5-nitrobenzene (CAS 858855-23-9)
- 1-(Chloromethyl)-2-methoxy-3-nitrobenzene (CAS 256455-93-3)
- 1-Chloro-4-ethoxy-2-nitrobenzene (CAS 89979-06-6)
- 4-Hydroxybenzo[c]phenanthrene (CAS 22717-96-0)
- n-((4-Bromothiophen-2-yl)methyl)-3-methoxypropan-1-amine (CAS 1152542-89-6)
- β-D-Fructofuranose, 1,6-bis(dihydrogen phosphate), trisodium salt (CAS 94333-58-1)
- 2,6-Dimethyl-4-[2-(phenylsulfanyl)acetyl]phenyl N,N-dimethylcarbamate (CAS 339101-02-9)
- 3-Chloro-4,5-diphenyl-4h-1,2,4-triazole (CAS 57022-97-6)
- 1-(4-Ethyl-6-oxo-1,6-dihydropyrimidin-2-yl)piperidine-4-carboxylic acid (CAS 1082392-86-6)
- Copper(II) oxalate xhydrate (CAS 23087-58-3)
- 2-(2-{[(4-chlorophenyl)sulfanyl]methyl}-1H-1,3-benzodiazol-1-yl)-N-(2,6-dimethylphenyl)acetamide (CAS 339100-96-8)
- 6-{2-[(4-fluoroanilino)carbothioyl]carbohydrazonoyl}-2,1,3-benzoxadiazol-1-ium-1-olate (CAS 286008-42-2)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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