6-Fluoro-N-(naphthalen-1-ylmethyl)-7-(piperazin-1-yl)quinazolin-4-amine CAS 625080-71-9
| CAS No. | 625080-71-9 |
| Molecular Formula | C23H22FN5 |
| Molecular Weight | 387.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Fluoro-N-(naphthalen-1-ylmethyl)-7-(piperazin-1-yl)quinazolin-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Fluoro-N-(naphthalen-1-ylmethyl)-7-(piperazin-1-yl)quinazolin-4-amine (CAS 625080-71-9) is a high-purity analytical reference standard with the molecular formula C23H22FN5 and a molecular weight of 387.45 g/mol.
Based on its molecular formula C23H22FN5, 6-Fluoro-N-(naphthalen-1-ylmethyl)-7-(piperazin-1-yl)quinazolin-4-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 387.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Fluoro-N-(naphthalen-1-ylmethyl)-7-(piperazin-1-yl)quinazolin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H22FN5 |
| Molecular Weight | 387.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- Fingolimod Phosphate (CAS 402615-91-2)
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- 3-Fluoro-2-methoxy-6-methylbenzaldehyde (CAS 1781804-36-1)
- N-(4-aminobenzyl)-N-methylacetamide (CAS 32578-17-9)
- Methyl 3,6-dicyclopropyl-1-(2-(ethylamino)-2-oxoethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018142-34-1)
- 5'-Bromospiro[cyclobutane-1,3'-indolin]-2'-one (CAS 304876-39-9)
- N-(2-Chloro-4-hydroxyphenyl)methanesulfonamide (CAS 1243289-17-9)
- Valproate Impurity 66 (CAS CATO-C4X-116666)
- 1-(3,4-Difluoro-5-(isopentyloxy)phenyl)propan-1-one (CAS 1443325-85-6)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(thiophen-2-yl)furan-2-yl)boronate (CAS 2223031-54-5)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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