3-Bromo-7-chloro-2-phenylpyrazolo[1,5-a]pyrimidine CAS 625095-83-2
| CAS No. | 625095-83-2 |
| Molecular Formula | C12H7BrClN3 |
| Molecular Weight | 308.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Bromo-7-chloro-2-phenylpyrazolo[1,5-a]pyrimidine (C12H7BrClN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
3-Bromo-7-chloro-2-phenylpyrazolo[1,5-a]pyrimidine (CAS 625095-83-2) is a high-purity analytical reference standard with the molecular formula C12H7BrClN3 and a molecular weight of 308.56 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7BrClN3 |
| Molecular Weight | 308.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
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Recommended Standards
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- 3-Bromo-2-chloro-4-methoxypyridine (CAS 144584-29-2)
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- Methyl 7-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate (CAS 919750-24-6)
- 1-(tert-Butyl)-3-cyclopropoxy-2-ethylbenzene (CAS 1243414-36-9)
- 6-Methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 138254-44-1)
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- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
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