1-(4-Amino-2-methylphenyl)pyrrolidine-2-thione CAS 625102-14-9

Purity 97%+In StockPharmaceutical Standards
CAS No.625102-14-9
Molecular FormulaC11H14N2S
Molecular Weight206.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Amino-2-methylphenyl)pyrrolidine-2-thione CAS 625102-14-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 206.31 g/mol gives 1-(4-Amino-2-methylphenyl)pyrrolidine-2-thione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(4-Amino-2-methylphenyl)pyrrolidine-2-thione (CAS 625102-14-9) is a high-purity analytical reference standard with the molecular formula C11H14N2S and a molecular weight of 206.31 g/mol.

The molecular framework of 1-(4-Amino-2-methylphenyl)pyrrolidine-2-thione (C11H14N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Amino-2-methylphenyl)pyrrolidine-2-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H14N2S
Molecular Weight206.31 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Nitrogen Atoms2
Sulfur Atoms1

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