N-{3-cyano-4H,5H,6H-cyclopenta[b]thiophen-2-yl}-2-{[3-cyano-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetamide CAS 625369-48-4
| CAS No. | 625369-48-4 |
| Molecular Formula | C25H19F3N4O3S2 |
| Molecular Weight | 544.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-{3-cyano-4H,5H,6H-cyclopenta[b]thiophen-2-yl}-2-{[3-cyano-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetamide (CAS 625369-48-4), molecular formula C25H19F3N4O3S2 and molecular weight 544.57 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, N-{3-cyano-4H,5H,6H-cyclopenta[b]thiophen-2-yl}-2-{[3-cyano-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 544.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), N-{3-cyano-4H,5H,6H-cyclopenta[b]thiophen-2-yl}-2-{[3-cyano-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H19F3N4O3S2 |
| Molecular Weight | 544.57 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related N Standards
- Ethyl 2-(2-((3-cyano-4-phenyl-6-(p-tolyl)pyridin-2-yl)thio)acetamido)-4,5-dimethylthiophene-3-carboxylate (CAS 332053-33-5)
- Ethyl 2-(2-((3-cyano-6-phenyl-4-(p-tolyl)pyridin-2-yl)thio)acetamido)-4,5-dimethylthiophene-3-carboxylate (CAS 332161-68-9)
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-(p-tolyl)pyridin-2-yl)thio)-N,N-diphenylacetamide (CAS 332114-45-1)
- Ethyl 4-cyano-5-(2-((3-cyano-6-(4-fluorophenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)acetamido)-3-methylthiophene-2-carboxylate (CAS 499208-69-4)
- 2-((3-Cyano-4-(3,4-dimethoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(2-methyl-4-nitrophenyl)acetamide (CAS 332177-59-0)
- 2-((3-Cyano-4-(3,4-dimethoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(2-methyl-5-nitrophenyl)acetamide (CAS 444152-30-1)
- 2-((3-Cyano-4-(4-ethoxy-3-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(4-nitrophenyl)acetamide (CAS 332162-69-3)
- 2-((3-Cyano-6-(4-ethoxyphenyl)-4-phenylpyridin-2-yl)thio)-N-(4-methoxy-2-nitrophenyl)acetamide (CAS 444152-73-2)
Recommended Standards
- Vilaprisan (CAS 1262108-14-4)
- (1R,2R)-2-(Acetyloxy)-1,2-diphenylethyl 2-(diphenylphosphino)benzoate (CAS 1220999-81-4)
- Cefamandole Impurity 7 (CAS CATO-C4X-12217)
- Tucatinib Impurity 55 (CAS CATO-C4X-260555)
- 5-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2,3-dimethylbenzoic acid (CAS 1342550-92-8)
- 1-Benzylpiperidine-4-carbohydrazide (CAS 74045-91-3)
- 4-(5-(1-Aminoethyl)-3-methylpyridin-2-yl)piperazine-1-carbaldehyde (CAS 1355226-08-2)
- 7-(3-Chlorophenyl)-2-(methylthio)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 1291487-05-2)
- Phytomenadione/Vitamin K1 Impurity 122 (CAS 571-63-1)
- N-Isopropyl-L-Z-Valinamide (CAS 61274-16-6)
- 1-(4-Chloropyrimidin-2-yl)piperidin-3-ol (CAS 916791-09-8)
- 3-{5-[(2E)-3-(4-chlorophenyl)prop-2-enoyl]-4-methyl-1,3-thiazol-2-yl}-1-methylpyridin-1-ium iodide (CAS 477712-99-5)
- 4-Ethoxy-5-methylpyrimidin-2-amine (CAS 248928-03-2)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
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