3-Amino-N-(2-bromo-4-methylphenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide CAS 625370-15-2
| CAS No. | 625370-15-2 |
| Molecular Formula | C21H22BrN3OS |
| Molecular Weight | 444.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-N-(2-bromo-4-methylphenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-N-(2-bromo-4-methylphenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 625370-15-2), molecular formula C21H22BrN3OS and molecular weight 444.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Amino-N-(2-bromo-4-methylphenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (C21H22BrN3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-N-(2-bromo-4-methylphenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H22BrN3OS |
| Molecular Weight | 444.39 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-N-(4-bromo-3-methylphenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 627056-84-2)
- 3-Amino-N-(2-methoxy-5-(trifluoromethyl)phenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 625370-66-3)
- Benzyl 2-amino-4-[(3-bromophenyl)methyl]-4H,5H,6H-pyrrolo[3,4-d][1,3]thiazole-5-carboxylate (CAS 1637310-51-0)
- 2-Amino-4-(4-methoxyphenyl)-7,7-dimethyl-1-(3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile (CAS 311318-23-7)
- 3-Amino-5-((2-carboxy-5-(isopentyloxy)phenyl)amino)-4-(isopentyloxy)benzoic acid (CAS 1096879-46-7)
- (R)-2-Amino-3-(hexylthio)propanoic acid (CAS 23884-44-8)
- 2-Amino-2-(4-((3-(benzyloxy)phenyl)thio)-2-chlorophenethyl)propane-1,3-diol (CAS 509092-16-4)
- 2-Amino-4-(4-chlorophenyl)-7,7-dimethyl-3-(phenylsulfonyl)-4,6,7,8-tetrahydro-5H-chromen-5-one (CAS 866137-52-2)
Recommended Standards
- 15-(4-Iodophenyl)pentadecanoic acid (CAS 80479-93-2)
- Formononetin 7-O-β-D-Glucuronide (CAS 18524-03-3)
- 5-Acetamino-4-hydroxy-2-(4-nitro-phenoxy)-6-(1,2,3-trihydroxy-propyl)- tetrahydro-pyran-2-carboxylic Acid Methyl Ester (CAS 59694-35-8)
- Methyl 2,6-bis((4,6-dimethoxypyrimidin-2-yl)oxy)benzoate (CAS 142966-13-0)
- 4-Bromo-3-fluoro-5-methoxypyridine (CAS 1256825-73-6)
- 1-{2-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl}-2-phenylethan-1-one (CAS 1795393-63-3)
- 2-(Ethyl(2-methoxybenzyl)amino)ethanol (CAS 104743-43-3)
- Methyl 3-nitro-4-[4-(2-thienylcarbonyl)piperazino]benzenecarboxylate (CAS 478246-65-0)
- n-((4-(Pyrrolidin-1-ylmethyl)thiazol-2-yl)methyl)propan-1-amine (CAS 1249833-56-4)
- 4-Methyl-2-((tert-pentylamino)methyl)phenol (CAS 1342501-65-8)
- 4-Methoxy-2,6-dimethylpyridine (CAS 20815-02-5)
- 3,5-Dibromo-1-(2-ethoxyethyl)-1H-1,2,4-triazole (CAS 1240579-95-6)
- methyl 3-(1,2,4-oxadiazol-5-yl)benzoate (CAS 1354951-60-2)
- Rac1 Inhibitor F56, control peptide (CAS 1315378-77-8)
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