7-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione CAS 625376-54-7
| CAS No. | 625376-54-7 |
| Molecular Formula | C18H10F3N3O4S |
| Molecular Weight | 421.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 625376-54-7), molecular formula C18H10F3N3O4S and molecular weight 421.35 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 7-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 421.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 7-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10F3N3O4S |
| Molecular Weight | 421.35 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dihydrobenzo Standards
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((3-(pyridin-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)acetamide (CAS 868969-87-3)
- 7-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4-hydroxy-9-(trifluoromethyl)thieno[2,3-b:4,5-b']dipyridin-2(1H)-one (CAS 626228-56-6)
- 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-(1-(3-(pyrazin-2-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)urea (CAS 1396679-82-5)
- N-(1-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-1H-pyrazol-4-yl)-5-(1,2-dithiolan-3-yl)pentanamide (CAS 1705877-03-7)
- 2-(5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)isoxazol-3-yl)-N-((5-(thiophen-2-yl)isoxazol-3-yl)methyl)acetamide (CAS 1171842-27-5)
- 1-(4-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)piperazin-1-yl)-2-phenoxyethan-1-one (CAS 847840-70-4)
- 2-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl (thiophene-2-carbonyl)prolinate (CAS 956202-97-4)
- 2-(((1-((2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)piperidin-4-yl)methyl)thio)-4-methylthiazole (CAS 1428356-69-7)
Recommended Standards
- 3-(Benzylthio)-1-(4-bromophenyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 439096-60-3)
- Apalutamide Impurity 30 (CAS CATO-C4X-274930)
- 3-Acetamido-6-acetyl-2-nitrophenyl 4-(dimethylamino)-3,5-difluorobenzoate (CAS 1548406-25-2)
- iso-Boc-His(Dnp)-OH (CAS 135409-37-9)
- Methyl (8-Methyl-4-oxoquinazolin-3(4H)-yl)acetate (CAS 1018239-14-9)
- 2,6,11,15-Tetramethylhexadecane (CAS 504-44-9)
- (S)-1-(4-Bromophenyl)-2,2,2-trifluoroethanamine (CAS 778565-93-8)
- tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate hydrochloride trihydrate (CAS 2368828-69-5)
- N-(4-Aminophenyl)-2-(2-isopropyl-5-methylphenoxy)-acetamide (CAS 954261-70-2)
- Methyl 2-{[2-(hydroxymethyl)phenyl]sulfanyl}acetate (CAS 34702-07-3)
- 5,5-Dimethyl-3-oxopyrazolidine-1-carboxamide (CAS 174470-58-7)
- Oxalic acid tert-Butyl N-(3-aminocyclopentyl)carbamate (CAS 1803597-18-3)
- Trimethyl(9-methyl-9H-fluoren-9-yl)germane (CAS 61857-68-9)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
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