2-((3-Cyano-6-(3-methoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide CAS 625377-09-5
| CAS No. | 625377-09-5 |
| Molecular Formula | C16H12F3N3O2S |
| Molecular Weight | 367.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-((3-Cyano-6-(3-methoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (C16H12F3N3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 367.35 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-((3-Cyano-6-(3-methoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 625377-09-5), a certified reference material (molecular formula C16H12F3N3O2S, MW 367.35 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((3-Cyano-6-(3-methoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl)thio)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12F3N3O2S |
| Molecular Weight | 367.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cyano Standards
- Ethyl 8-cyano-7-methoxy-2-(phenylthiomethyl)imidazo[1,2-a]pyridine-3-carboxylate (CAS 1704066-58-9)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 2-(methylsulfonamido)benzoate (CAS 877127-30-5)
- N-[3-Cyano-4-(4-methylphenyl)-4H-benzo[h]chromen-2-yl]-N,N-dimethyliminoformamide (CAS 860787-52-6)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio)acetamide (CAS 847840-90-8)
- N-(3-Cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-2-(methyl(4-methylbenzyl)amino)acetamide (CAS 879837-43-1)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 3-chloroadamantane-1-carboxylate (CAS 878260-86-7)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 2-(4-chlorophenoxy)-2-methylpropanoate (CAS 877974-12-4)
- 2-[1-Cyano-2-(2,4-dichlorophenyl)vinyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 338977-22-3)
Recommended Standards
- 13-Hydroxy-9,10-dimethoxy-5,6-dihydro-8H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-8-one (CAS 66408-27-3)
- 2-(2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)-4-phenylthiazol-5-yl)acetic acid (CAS 955976-94-0)
- (S)-5-(Benzyloxy)-2-(1,3-dioxoisoindolin-2-yl)-5-oxopentanoic acid (CAS 88784-33-2)
- 2-(3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl)-N-(pyridin-3-ylmethyl)thiazole-4-carboxamide (CAS 957039-48-4)
- 4-fluoro-1H-indazole-6-carbonitrile (CAS 1082041-49-3)
- 1-Methyl-N-phenylcyclopropanecarboxamide (CAS 102587-29-1)
- 3-Methyl-2-(2-(trifluoromethyl)phenyl)butanoic acid (CAS 1225487-35-3)
- 9-Allyl-2-(4-(3,3,3-triphenylpropyl)piperazin-1-yl)-9H-purine dimethanesulfonate (CAS 37425-13-1)
- 3-(3-Iodo-1H-1,2,4-triazol-1-yl)tetrahydrothiophene 1,1-dioxide (CAS 1520131-57-0)
- N-[2-(2-amino-1,3-thiazol-4-yl)-5-fluorophenyl]acetamide (CAS 878259-58-6)
- 8-Ethoxyquinolin-2-amine (CAS 635755-43-0)
- 1,3,5-Tris(4-bromophenyl)-1,3,5-triazinane (CAS 102310-99-6)
- 6-Bromo-3-methoxy-2-nitrobenzoic Acid (CAS 127971-97-5)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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