6-Cyclopropyl-2-(ethylthio)-4-(trifluoromethyl)nicotinonitrile CAS 625377-26-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Cyclopropyl-2-(ethylthio)-4-(trifluoromethyl)nicotinonitrile.

6-Cyclopropyl-2-(ethylthio)-4-(trifluoromethyl)nicotinonitrile (CAS 625377-26-6) is a high-purity analytical reference standard with the molecular formula C12H11F3N2S and a molecular weight of 272.29 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, 6-Cyclopropyl-2-(ethylthio)-4-(trifluoromethyl)nicotinonitrile is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 272.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-Cyclopropyl-2-(ethylthio)-4-(trifluoromethyl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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