2-((5-Cyano-4-(trifluoromethyl)-[2,4'-bipyridin]-6-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide CAS 625378-14-5
| CAS No. | 625378-14-5 |
| Molecular Formula | C22H15F3N4O3S |
| Molecular Weight | 472.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((5-Cyano-4-(trifluoromethyl)-[2,4'-bipyridin]-6-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((5-Cyano-4-(trifluoromethyl)-[2,4'-bipyridin]-6-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 625378-14-5) is a high-purity analytical reference standard with the molecular formula C22H15F3N4O3S and a molecular weight of 472.44 g/mol.
2-((5-Cyano-4-(trifluoromethyl)-[2,4'-bipyridin]-6-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (C22H15F3N4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H15F3N4O3S |
| Molecular Weight | 472.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Cyano Standards
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- Ethyl 2-cyano-3-(3-methoxy-4-(2-oxo-2-((4-phenoxyphenyl)amino)ethoxy)phenyl)acrylate (CAS 337924-92-2)
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(5-methylthiazol-2-yl)acetamide (CAS 332101-70-9)
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- 2-{[3-cyano-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl]sulfanyl}-N-[(3,4-dichlorophenyl)methyl]acetamide (CAS 626227-67-6)
- 2-{[3-cyano-6-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-2-phenylacetic acid (CAS 939888-61-6)
- Methyl 2-((2-cyano-2-(4-(6-nitro-2-oxo-2H-chromen-3-yl)thiazol-2-yl)vinyl)amino)benzoate (CAS 799776-34-4)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((5-(pyridin-3-yl)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 757215-99-9)
Recommended Standards
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- Entero-Hylambatin (CAS 198541-90-1)
- tert-butyl (3R)-3-(methoxymethyl)piperazine-1-carboxylate (CAS 1359658-32-4)
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- 1,4-Benzenedicarboxylic acid,2,3-dihydroxy-,1,4-dihydrazide (CAS 887576-09-2)
- Cefazolin Impurity 52 (CAS CATO-C4X-157752)
- 4-Isopropoxy-4-phenylbutanenitrile (CAS 70289-00-8)
- N-Benzyl-4-chloro-6-methylpyrimidin-2-amine (CAS 25710-11-6)
- 4-Bromo-N-(3-isopropoxypropyl)-1h-pyrrole-2-carboxamide (CAS 1197527-54-0)
- 1-(2-Hydroxyphenyl)-2-methoxyethanone (CAS 138206-45-8)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
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