2-(4-Chlorophenyl)-2-methylpropanoic Acid CAS 6258-30-6
| CAS No. | 6258-30-6 |
| Molecular Formula | C10H11ClO2 |
| Molecular Weight | 198.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Chlorophenyl)-2-methylpropanoic Acid.
2-(4-Chlorophenyl)-2-methylpropanoic Acid (CAS 6258-30-6), molecular formula C10H11ClO2 and molecular weight 198.65 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Chlorophenyl)-2-methylpropanoic Acid (C10H11ClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Chlorophenyl)-2-methylpropanoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO2 |
| Molecular Weight | 198.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 3-(4-Chlorophenyl)-2-methylpropanoic acid (CAS 1012-17-5)
- Methyl 2-(3-chlorophenyl)propanoate (CAS 103040-42-2)
- Methyl 3-(3-chlorophenyl)propanoate (CAS 103040-43-3)
- 3-(4-CHlorophenyl)propanehydrazide (CAS 1132-73-6)
- Methyl 2-(2-chlorophenyl)propanoate (CAS 115615-35-5)
- (E)-3-(4-chlorophenyl)-N'-hydroxypropanimidamide (CAS 1219625-88-3)
- 3-(3-Chlorophenyl)butanoic acid (CAS 1226163-60-5)
- Ethyl 2-(4-Chlorophenyl)acetate (CAS 14062-24-9)
Recommended Standards
- 2-(4-Chlorophenyl)-2-methyl-1,3-dioxolane (CAS 36881-02-4)
- 2-(4-Chlorophenyl)butanoic acid (CAS 29645-00-9)
- 2-(4-Chlorophenyl)-2-(methylamino)acetamide (CAS 71972-39-9)
- 2-(4-Methoxy-3-methylphenyl)acetyl chloride (CAS 4513-72-8)
- Ethyl 2-((4-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-3-oxo-7-(trifluoromethyl)-3,4-dihydroquinoxalin-2-yl)thio)acetate (CAS 337921-06-9)
- (S)-2-Amino-N-cyclopropyl-N-(2-oxo-2-(thiazol-2-yl)ethyl)propanamide (CAS 1354004-41-3)
- Propargyl-PEG1-THP (CAS 119096-95-6)
- 8-Bromo-6-fluoro-2h-chromene-3-sulfonyl chloride (CAS 1235439-52-7)
- Diethyl 1-benzyl-1H-imidazole-4,5-dicarboxylate (CAS 1232-51-5)
- N-(4-carbamoylphenyl)-1-(3,4-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide (CAS 892714-95-3)
- 2-Hydroxy-6-(trifluoromethyl)pyridine-4-acetic acid (CAS 1227601-77-5)
- Zirconium(IV) diisopropoxidebis(2,2,6,6-tetramethyl-3,5-heptanedionate) (CAS 204522-78-1)
- Haloperidol Impurity 16 (CAS 40807-61-2)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
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