Leuprorelin EP Impurity A TFA CAS 62621-13-0
| CAS No. | 62621-13-0 |
| Molecular Formula | C59H84N16O12 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Leuprorelin EP Impurity A TFA is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Leuprorelin EP Impurity A TFA (CAS 62621-13-0, C59H84N16O12C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C59H84N16O12C2HF3O2, Leuprorelin EP Impurity A TFA contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 1323.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C59H84N16O12 C2HF3O2 |
| Molecular Weight | 1323.44 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 26.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 16 |
Related Leuprorelin Standards
- Leuprorelin impurity 37 (CAS 112642-11-2)
- Leuprorelin EP Impurity B Trifluoroacetic acid (CAS 112642-11-2 (free base))
- Leuprorelin Impurity N8 (CAS 112642-11-2（free base）)
- Leuprorelin EP Impurity G (CAS 112710-57-3)
- Leuprorelin EP Impurity G Trifluoroacetic acid (CAS 112710-57-3(free base))
- Leuprorelin EP Impurity H (CAS 112710-58-4)
- Leuprorelin EP Impurity H Trifluoroacetic acid (CAS 112710-58-4(free base))
- Leuprorelin Impurity 14 (CAS 129244-90-2)
Recommended Standards
- Linezolid Impurity 15 (CAS 93246-53-8)
- Roxadustat Impurity 81 (CAS CATO-C4X-221381)
- Losartan Impurity 53 (CAS 2904682-23-9)
- 2-(Ethylamino)-5-(trifluoromethyl)benzonitrile (CAS 1094243-48-7)
- N-(4-Hydroxy-3-(4-methylpiperazin-1-yl)phenyl)-2'-methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)-[1,1'-biphenyl]-4-carboxamide (CAS 256227-77-7)
- 3-Amino-1-((4-methyl-1,2,5-oxadiazol-3-yl)methyl)pyridin-2(1h)-one (CAS 1341626-79-6)
- 1-(furan-3-sulfonyl)piperazine (CAS 1334149-30-2)
- N-Allyl-4-piperidinecarboxamide hydrochloride (CAS 1219957-31-9)
- 2-(6-Amino-1h-indazol-1-yl)acetonitrile (CAS 210581-44-5)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com