N-(3-chloro-4-fluorophenyl)-2-((3-cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)acetamide CAS 626227-14-3
| CAS No. | 626227-14-3 |
| Molecular Formula | C18H12ClF4N3OS |
| Molecular Weight | 429.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
N-(3-chloro-4-fluorophenyl)-2-((3-cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)acetamide (CAS 626227-14-3) is a high-purity analytical reference standard with the molecular formula C18H12ClF4N3OS and a molecular weight of 429.82 g/mol.
N-(3-chloro-4-fluorophenyl)-2-((3-cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio)acetamide (C18H12ClF4N3OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12ClF4N3OS |
| Molecular Weight | 429.82 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
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Recommended Standards
- Methyl 4-[(2-{[(4-chlorophenyl)carbamoyl]amino}-4-(trifluoromethyl)phenyl)amino]butanoate (CAS 339101-65-4)
- N-[(1E)-{[(2-chloro-4-fluorophenyl)methoxy]imino}methyl]-4-methoxy-2-phenoxypyridine-3-carboxamide (CAS 478262-47-4)
- 6-Amino-N-(3-chloro-4-fluorophenyl)-8-(trifluoromethyl)-4-thia-2-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,5,7-tetraene-5-carboxamide (CAS 626227-22-3)
- Cloransulam-Methyl (CAS 147150-35-4)
- Ethyl 2-(3,5-di(pyridin-2-yl)-1H-1,2,4-triazol-1-yl)acetate (CAS 1171933-03-1)
- 4-Cyano-2,5-dimethylbenzene-1-sulfonyl chloride (CAS 1804897-73-1)
- 4-methyl-1-[3-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)propyl]-1H-pyrazol-3-amine (CAS 1174854-93-3)
- Diethyl (2S,3S)-oxirane-2,3-dicarboxylate (CAS 73890-18-3)
- 5,6-Dichloro-n,n-dimethylpyridine-3-carboxamide (CAS 915949-03-0)
- 2-(3-(4-Chlorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)-2-oxoethyl 2-(methylthio)nicotinate (CAS 473671-25-9)
- Acetazolamide-d3 (CAS 1189904-01-5)
- 2-(Chloromethyl)imidazo[1,2-b]pyridazine dihydrochloride (CAS 154578-21-9)
- 6-(Indolin-1-yl)-4-methylnicotinaldehyde (CAS 1355182-19-2)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
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