3-Amino-N-(3-cyanophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide CAS 626228-78-2
| CAS No. | 626228-78-2 |
| Molecular Formula | C21H17F3N4OS |
| Molecular Weight | 430.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Amino-N-(3-cyanophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide (C21H17F3N4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-Amino-N-(3-cyanophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 626228-78-2) is a high-purity analytical reference standard with the molecular formula C21H17F3N4OS and a molecular weight of 430.45 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Amino-N-(3-cyanophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H17F3N4OS |
| Molecular Weight | 430.45 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 2-(4-Phenylpiperazin-1-yl)-5-(thiophen-2-yl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 691873-00-4)
- 4,4'-((2,5-Dimethoxy-1,4-phenylene)bis(ethene-2,1-diyl))dibenzoic acid (CAS 67546-17-2)
- cis-4-fluoropiperidin-3-ol;hydrochloride (CAS 1638765-12-4)
- N-(3-Fluorobenzyl)-2-(trifluoromethyl)aniline (CAS 1042510-31-5)
- 2-amino-6-ethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol (CAS 392315-45-6)
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- Benzyl N-(carbamimidoylmethyl)carbamate (CAS 77390-81-9)
- [D-His1]-Semaglutide (CAS CATO-C4X-2226127)
Why CATO?
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