Ro 106-9920 CAS 62645-28-7
| CAS No. | 62645-28-7 |
| Molecular Formula | C10H7N5OS |
| Molecular Weight | 245.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ro 106-9920 (CAS 62645-28-7), molecular formula C10H7N5OS and molecular weight 245.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ro 106-9920 (C10H7N5OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ro 106-9920 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7N5OS |
| Molecular Weight | 245.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Recommended Standards
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- Lamivudine Impurity 1 (CAS 1235712-40-9)
- N,N-Dimethyl-N′-(3-nitrophenyl)sulfamide (CAS 82936-48-9)
- Lamivudine Impurity 18 (CAS CATO-C4X-119418)
- 1-(3,5-Dimethylphenyl)-1h,4h,5h-pyrazolo[3,4-d]pyrimidin-4-one (CAS 852840-43-8)
- 6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 16821-32-2)
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- 2-Chloro-4-fluoro-6-nitrophenol (CAS 58348-98-4)
- N-(3,5-dichlorophenyl)-2-((5-methyl-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 306730-38-1)
- Clindamycin Phosphate Sulfoxide Impurity (CAS 1228573-90-7)
- 2-(1,2,3-Thiadiazol-5-yloxy)quinoxaline (CAS 866136-87-0)
- 4-Bromo-3-methyl-7-azaindole (CAS 1363382-02-8)
- Neratinib Impurity 36 (CAS CATO-C4X-113436)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
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