6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride CAS 6266-97-3
| CAS No. | 6266-97-3 |
| Molecular Formula | C12H18NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (C12H18NO2Cl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 6266-97-3), a certified reference material (molecular formula C12H18NO2Cl, MW 243.73 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H18NO2 Cl |
| Molecular Weight | 243.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dimethoxy Standards
- 6,7-Dimethoxy-1,4-phthalazinediol (CAS 10001-35-1)
- 6,7-Dimethoxy-4-methylphthalazin-1(2H)-one (CAS 10001-36-2)
- 3-Benzyl-9,9-dimethoxy-3-azabicyclo[3.3.1]nonane (CAS 1000931-10-1)
- 4,7-Dimethoxy-1-methylquinolin-2(1H)-one (CAS 100192-50-5)
- 2-(4,5-Dimethoxy-2-nitrophenyl)succinic acid (CAS 100193-44-0)
- 2,7-dimethoxy-1,5-naphthyridine (CAS 1003944-36-2)
- 6,7-Dimethoxy-1H-indene-3-carbonitrile (CAS 100449-12-5)
- 5-(5,6-Dimethoxy-1H-benzo[d]imidazol-1-yl)-3-((2-(methylsulfonyl)benzyl)oxy)thiophene-2-carboxylic acid (CAS 1007698-63-6)
Recommended Standards
- 4,5-Difluoro-3,3-dimethylindolin-2-one (CAS 1159009-98-9)
- (R)-(+)-Citronellic Acid (CAS 18951-85-4)
- 4-Hydroxy-2-(hydroxymethyl)benzimidazole (CAS 116345-47-2)
- N-allyl-5-chlorofuran-2-carboxamide (CAS 1197799-95-3)
- tert-Butyl 3-(2-((methylsulfonyl)oxy)ethyl)azetidine-1-carboxylate (CAS 958026-60-3)
- 3-Bromo-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine (CAS 116233-20-6)
- 5-(1-Methylpiperidin-2-yl)-1H-indole (CAS 1355219-90-7)
- 3-Methoxymorphinan Hydrochloride (CAS 36397-14-5)
- 2-(4-Methoxybenzyl)azepane (CAS 68841-06-5)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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