3-Amino-N,N-dimethylbenzenesulfonamide CAS 6274-18-6
| CAS No. | 6274-18-6 |
| Molecular Formula | C8H12N2O2S |
| Molecular Weight | 200.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Amino-N,N-dimethylbenzenesulfonamide (CAS 6274-18-6), a certified reference material (molecular formula C8H12N2O2S, MW 200.26 g/mol) for analytical method development and quality control.
The molecular framework of 3-Amino-N,N-dimethylbenzenesulfonamide (C8H12N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-N,N-dimethylbenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12N2O2S |
| Molecular Weight | 200.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-4,5-dimethylbenzene-1-sulfonamide (CAS 101251-33-6)
- 4-Amino-n,2-dimethylbenzene-1-sulfonamide (CAS 101252-52-2)
- 3-amino-N,4-dimethylbenzene-1-sulfonamide (CAS 1017450-04-2)
- 3-Amino-2,4-dimethylbenzene-1-sulfonamide (CAS 10311-44-1)
- 2-Amino-4,5-dimethylbenzene-1-sulfonamide (CAS 1042519-80-1)
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- 4-Amino-3-(2-thienyl)-benzonitrile (CAS 1075253-81-4)
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Recommended Standards
- 3-Amino-5-phenylthiophene-2-carbonitrile (CAS 83060-72-4)
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- 3-Ethyl-2-(ethylthio)-6-hydroxypyrimidin-4(3H)-one (CAS 415714-24-8)
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- 5-(6-Methylpyridin-2-yl)-1,3,4-thiadiazol-2-amine (CAS 1019528-02-9)
- 2-oxa-8-azaspiro[4.5]decan-4-ol;hydrochloride (CAS 374795-07-0)
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- Tert-butyl (4-(4-aminophenoxy)phenethyl)carbamate (CAS 866114-35-4)
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