(8-Fluoroquinolin-4-yl)methanol CAS 627463-73-4
| CAS No. | 627463-73-4 |
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(8-Fluoroquinolin-4-yl)methanol (CAS 627463-73-4) is a high-purity analytical reference standard with the molecular formula C10H8FNO and a molecular weight of 177.18 g/mol.
The molecular framework of (8-Fluoroquinolin-4-yl)methanol (C10H8FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoroquinolin Standards
- (6-Fluoroquinolin-8-yl)methanol (CAS 1153757-10-8)
- (5-Fluoroquinolin-8-yl)methanol (CAS 1153758-16-7)
- (8-Fluoroquinolin-3-yl)methanol (CAS 1307240-33-0)
- (7-Fluoroquinolin-8-yl)methanol (CAS 1540095-36-0)
- (8-Fluoroquinolin-2-yl)methanol (CAS 165111-40-0)
- (6-Fluoroquinolin-3-yl)methanamine (CAS 1196146-75-4)
- (8-fluoroquinolin-3-yl)methanamine (CAS 1267242-11-4)
- (6-Fluoroquinolin-8-yl)methanamine (CAS 1367804-71-4)
Recommended Standards
- 1-(6-Fluoro-1H-indol-5-yl)ethanone (CAS 1956377-71-1)
- 1-(2-Fluorophenyl)-1H-pyrazol-3-amine (CAS 685094-07-9)
- 7-Fluoro-1-methylquinolin-2(1H)-one (CAS 1936591-26-2)
- 1-(4-Fluoro-1h-indol-3-yl)ethan-1-one (CAS 949035-25-0)
- 3-Cyclopropoxy-5-isopropyl-N-methylaniline (CAS 1243350-07-3)
- N-((1-(Benzo[d]thiazol-2-yl)piperidin-4-yl)methyl)-5-phenylisoxazole-3-carboxamide (CAS 1797953-61-7)
- 1-Ethyl-n,2-dimethylpiperidin-4-amine (CAS 93438-92-7)
- 4-(Pentafluoroethyl)benzene-1-sulfonyl chloride (CAS 884010-48-4)
- 6-Chloro-4-phenylpyridin-2-ol (CAS 25297-48-7)
- Methyl 4-[4-(benzyloxy)phenyl]-3-methoxybenzoate (CAS 1820641-68-6)
- N,N'-(2-Nitro-3-(pyrrolidin-1-yl)-1,4-phenylene)diacetamide (CAS 110209-28-4)
- MEthyl 1-(4-chlorophenyl)-2,3,4,9-tetrahydro-1h-beta-carboline-3-carboxylate, HCl (CAS 1214644-75-3)
- Diisopropyl 3-oxocyclobutane-1,1-dicarboxylate (CAS 893724-10-2)
- C-Peptide 2 (rat) (CAS 41594-08-5)
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