2-(3-(1,1-Difluoroethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 627526-11-8
| CAS No. | 627526-11-8 |
| Molecular Formula | C14H18BF3O2 |
| Molecular Weight | 286.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3-(1,1-Difluoroethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 627526-11-8), molecular formula C14H18BF3O2 and molecular weight 286.10 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C14H18BF3O2, 2-(3-(1,1-Difluoroethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.10 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H18BF3O2 |
| Molecular Weight | 286.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Difluoroethyl Standards
- 2-(2-(1,1-Difluoroethyl)-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2222553-85-5)
- 2-(3-(1,1-Difluoroethyl)-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 445303-68-4)
- 2,2-Difluoroethyl (4,4,5,5,5-pentafluoropentyl) carbonate (CAS 1980040-02-5)
- 1-(2,2-Difluoroethyl)-4-iodo-3,5-dimethyl-1H-pyrazole (CAS 1354705-34-2)
- 1-(2,2-Difluoroethyl)-4-iodo-5-methyl-1H-pyrazol-3-amine (CAS 1354706-79-8)
- Methyl 5-(4-(1,1-difluoroethyl)phenyl)piperidine-3-carboxylate (CAS 1256841-57-2)
- 4-({[1-(2,2-difluoroethyl)-1H-pyrazol-4-yl]amino}methyl)-2-methoxyphenol (CAS 1172971-94-6)
- n-(2,2-Difluoroethyl)-3-iodoaniline (CAS 1184404-75-8)
Recommended Standards
- 2-(5-(Difluoromethyl)-3-fluoro-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2856022-19-8)
- 3-Bromo-5-fluoro-1-(4-methoxybenzyl)-1H-1,2,4-triazole (CAS 2795110-35-7)
- 2-(1-Aminoethyl)-3-bromo-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 918422-25-0)
- 4,4,5,5-Tetramethyl-2-(2-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane (CAS 475250-54-5)
- 1-(1-Methyl-2-(methylthio)-1H-imidazol-4-yl)ethanone (CAS 177910-95-1)
- Ethyl (1R,2S,4S)-4-amino-2-methylcyclohexane-1-carboxylate (CAS 1411772-62-7)
- 8-Ethyl-3,4-dihydroquinolin-2(1H)-one (CAS 165592-45-0)
- 1-Morpholinobutane-1,3-dione (CAS 16695-54-8)
- Cefodizime Impurity 16 (CAS CATO-C4X-180616)
- 4-Chloro-3-nitrocoumarin (CAS 38464-20-9)
- N-{3-[2-(methylamino)-1,3-thiazol-4-yl]phenyl}hexanamide (CAS 866040-78-0)
- 5-Bromo-7-fluoroindole-3-acetic Acid (CAS 1019111-81-9)
- 7-Methoxychroman-2-one (CAS 20921-02-2)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com