5-(Chloromethyl)-1,3,4-thiadiazol-2-amine CAS 62774-00-9
| CAS No. | 62774-00-9 |
| Molecular Formula | C3H4ClN3S |
| Molecular Weight | 149.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(Chloromethyl)-1,3,4-thiadiazol-2-amine is closely related to a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-(Chloromethyl)-1,3,4-thiadiazol-2-amine (CAS 62774-00-9), a certified reference material (molecular formula C3H4ClN3S, MW 149.60 g/mol) for analytical method development and quality control.
5-(Chloromethyl)-1,3,4-thiadiazol-2-amine (C3H4ClN3S) contains a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H4ClN3S |
| Molecular Weight | 149.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
- 3-(Chloromethyl)-1,2,4-thiadiazol-5-amine (CAS 112807-11-1)
- 6-(chloromethyl)pyridazin-3-amine (CAS 1314905-08-2)
- 4-(Chloromethyl)piperidin-4-ol (CAS 133231-26-2)
- 2-(chloromethyl)-4-methylmorpholine (CAS 40987-31-3)
- 5-(chloromethyl)pyrimidin-2-amine (CAS 769083-57-0)
- N-(Chloromethyl)-N-methylisobutyramide (CAS 51164-43-3)
- N-[1-(chloromethyl)propyl]acetamide (CAS 59173-61-4)
- (R)-4-(Chloromethyl)oxazolidine-2,5-dione (CAS 135920-56-8)
Recommended Standards
- 4-Chloro-3-methoxyisothiazole (CAS 78383-41-2)
- 5-Chloro-3-(methylthio)-1H-1,2,4-triazole (CAS 51108-40-8)
- 4-Chloro-2-methylisothiazol-3(2H)-one (CAS 71091-90-2)
- 5-Chloro-N-methyl-1,3,4-thiadiazol-2-amine (CAS 68429-94-7)
- Isobutyramide (CAS 563-83-7)
- N,N-dimethylfuran-2-carboxamide (CAS 13156-75-7)
- N-(4-(heptyloxy)phenyl)acetamide (CAS 55792-60-4)
- 2H-Pyran-2-amine (CAS 83372-63-8)
- Bilastine impurity 110 (CAS CATO-C4X-2253110)
- 6-Amino-n,n-dimethylpyridine-3-carboxamide (CAS 827588-33-0)
- 1-Azaspiro[3.3]heptane (CAS 51392-72-4)
- 3-(Cinnamylthio)-5-(2,4-dichlorophenyl)-4H-1,2,4-triazol-4-amine (CAS 675131-44-9)
- 3-Nitro-1h-pyrazole-5-carboxamide (CAS 297149-32-7)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
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