Methyl 2-(2-fluoro-5-hydroxyphenyl)acetate CAS 628333-59-5
| CAS No. | 628333-59-5 |
| Molecular Formula | C9H9FO3 |
| Molecular Weight | 184.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2-(2-fluoro-5-hydroxyphenyl)acetate.
Methyl 2-(2-fluoro-5-hydroxyphenyl)acetate (CAS 628333-59-5), molecular formula C9H9FO3 and molecular weight 184.16 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 2-(2-fluoro-5-hydroxyphenyl)acetate (C9H9FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 2-(2-fluoro-5-hydroxyphenyl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9FO3 |
| Molecular Weight | 184.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Methyl Standards
- 3-fluoro-4-(2-hydroxyethoxy)benzaldehyde (CAS 1004779-24-1)
- 2-(3-Fluoro-2-methoxyphenyl)acetic acid (CAS 1017778-30-1)
- Ethyl 2-fluoro-3-hydroxybenzoate (CAS 105836-28-0)
- Methyl 3-fluoro-2-methoxybenzoate (CAS 106428-04-0)
- 1-(2-Fluoro-4-hydroxy-5-methoxyphenyl)ethan-1-one (CAS 1065076-49-4)
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Recommended Standards
- Methyl (R)-2-(2-fluorophenyl)-2-hydroxyacetate (CAS 32174-36-0)
- Methyl 2-(3-fluoro-2-hydroxyphenyl)acetate (CAS 628330-77-8)
- Methyl (2s)-2-(4-fluorophenyl)-2-hydroxyacetate (CAS 63096-35-5)
- Methyl 2-(3-fluoro-4-hydroxyphenyl)acetate (CAS 79280-92-5)
- 3-Fluoro-4-(2-(pyrrolidin-1-yl)ethoxy)aniline (CAS 837421-94-0)
- Tert-butyl (S)-(1-oxo-1-(piperazin-1-yl)propan-2-yl)carbamate (CAS 205189-94-2)
- methyl 1,4-oxazepane-7-carboxylate (CAS 1782530-62-4)
- 5-Isobutylimidazolidine-2,4-dione (CAS 67337-73-9)
- 8-Amino-5-bromoquinoline-7-carboxylic acid (CAS 914208-07-4)
- Ethyl 2-(3-(difluoromethyl)-5,5-difluoro-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetate (CAS 1626337-84-5)
- 4-(Benzo[d]thiazol-2-yl)-N-methylbutan-1-amine (CAS 933713-77-0)
- N-(4-chlorophenyl)-4-(1-methyl-6-(methylamino)-3,5-dinitro-1,4-dihydropyridin-2-yl)piperazine-1-carboxamide (CAS 339020-75-6)
- Tiotropium Bromide EP Impurity H-d3 Bromide (Mixture of Enantiomers) (CAS 1044148-31-3（unlabeled）)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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