8-Fluoro-7-(trifluoromethyl)imidazo[1,2-a]pyridine CAS 628692-23-9
| CAS No. | 628692-23-9 |
| Molecular Formula | C8H4F4N2 |
| Molecular Weight | 204.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
8-Fluoro-7-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 628692-23-9) is a high-purity analytical reference standard with the molecular formula C8H4F4N2 and a molecular weight of 204.12 g/mol.
Based on its molecular formula C8H4F4N2, 8-Fluoro-7-(trifluoromethyl)imidazo[1,2-a]pyridine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 204.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 8-Fluoro-7-(trifluoromethyl)imidazo[1,2-a]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4F4N2 |
| Molecular Weight | 204.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 2-Fluoro-4-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1227511-79-6)
- 2-Fluoro-5-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1227512-10-8)
- 2-Fluoro-3-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1227513-68-9)
- 6-Fluoro-2-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1227514-04-6)
- 3-Fluoro-2-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1227514-88-6)
- 2-Fluoro-6-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1227580-08-6)
- 3-Fluoro-5-(trifluoromethyl)pyridine-2-acetonitrile (CAS 1227592-18-8)
- 2-Fluoro-5-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1227600-17-0)
Recommended Standards
- 5-Fluoro-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 3671-47-4)
- Ethyl (2,2,3,3-tetrafluoropropyl) carbonate (CAS 277332-97-5)
- 4-Ethynyl-2-fluoro-1-(trifluoromethoxy)benzene (CAS 912617-68-6)
- Hydroxymethyl resin (200-400 mesh, 0.9-1.4 mmol/g) (CAS 66072-40-0)
- 2-Bromo-8-(trifluoromethoxy)quinoline (CAS 1352443-24-3)
- tert-Butyl 3-amino-3-phenylazetidine-1-carboxylate (CAS 1445781-95-2)
- 2-Fluoro-6-methylphenyl acetate (CAS 443-34-5)
- 2-(2,4-Dimethylphenyl)phthalazin-1(2H)-one (CAS 930899-16-4)
- 4-(Sulfooxy)dibenz[b,f][1,4]oxazepin-11(10H)-one (CAS 88373-19-7)
- Methyl 2-Amino-2-(4-tetrahydropyranyl)acetate (CAS 477585-43-6)
- 3-(Methylamino)-N,3-dimethyl-butanamide (CAS 859195-79-2)
- 3-(4-Methoxyphenoxy)-5-nitroaniline (CAS 832739-76-1)
- 2,6-Dimethylpyridine-3,4-dicarboxylic acid (CAS 13602-84-1)
- Des-Leu14-Tirzepatide (CAS CATO-CPTD788959)
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