4-(3,5-Dichloro-4-methylphenyl)-4-oxobutanoic acid CAS 62903-05-3
| CAS No. | 62903-05-3 |
| Molecular Formula | C11H10Cl2O3 |
| Molecular Weight | 261.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(3,5-Dichloro-4-methylphenyl)-4-oxobutanoic acid (CAS 62903-05-3), molecular formula C11H10Cl2O3 and molecular weight 261.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(3,5-Dichloro-4-methylphenyl)-4-oxobutanoic acid (C11H10Cl2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(3,5-Dichloro-4-methylphenyl)-4-oxobutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10Cl2O3 |
| Molecular Weight | 261.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
Related Dichloro Standards
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Recommended Standards
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- Tert-butyl 3-amino-2,2-dimethylpyrrolidine-1-carboxylate (CAS 1492530-75-2)
- 1185300-46-2 [(4-Methylphenyl)(4-pyridinyl)methyl]amine dihydrochloride MFCD08448121 (CAS 1185300-46-2)
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- 1-(Hydroxyimino)-1-(pyridin-2-yl)propan-2-one (CAS 65882-98-6)
- 71189-23-6 A837108 sodium 3-[[2-(4-hydroxyphenyl)sulfonyl-5-oxidanyl-phenyl]methyl]naphthalene-2-sulfonate sodium 3-[[5-hydroxy-2-(4-hydroxyphenyl)sulfonylphenyl]methyl]-2-naphthalenesulfonate (CAS 71189-23-6)
- 4-Amino-n,n-dimethylbutanamide hydrochloride (CAS 156337-81-4)
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