3-(tert-Butyl)-2-hydroxy-5-methoxybenzoic acid CAS 6291-15-2
| CAS No. | 6291-15-2 |
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(tert-Butyl)-2-hydroxy-5-methoxybenzoic acid (CAS 6291-15-2) is a high-purity analytical reference standard with the molecular formula C12H16O4 and a molecular weight of 224.25 g/mol.
3-(tert-Butyl)-2-hydroxy-5-methoxybenzoic acid (C12H16O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-(tert-Butyl)-2-hydroxy-5-methoxybenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16O4 |
| Molecular Weight | 224.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Recommended Standards
- 3-(p-Tolyl)isobenzofuran-1(3H)-one (CAS 21615-75-8)
- 3,3-Diphenylacrylic acid (CAS 606-84-8)
- 3-(o-Tolyl)isobenzofuran-1(3H)-one (CAS 90445-44-6)
- 3,4-dimethoxy-5-propylbenzoic acid (CAS 199484-26-9)
- 5,7-Dichloro-3-iodo-1H-indazole (CAS 885271-35-2)
- 2-Carboxy-3-fluorophenylboronic acid (CAS 1799979-96-6)
- 2-(1-(Difluoromethyl)-1h-pyrazol-4-yl)aniline (CAS 1341933-23-0)
- 1-((P-tolylamino)methyl)cyclopentan-1-ol (CAS 1482692-94-3)
- 2,4-Dichloro-6-iodoquinazoline, 97% (CAS 74173-76-5)
- Vorapaxar Impurity 3 (CAS 618385-10-7)
- Methyl 4-Chloro-2-methoxy-5-methylbenzoate (CAS 1368228-61-8)
- Ropivacaine Impurity 19 (CAS 1817657-89-8)
- (3,4-Difluorophenyl)thiourea (CAS 883091-83-6)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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